SF3B1 anticorps (AA 1-100)
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- Antigène Voir toutes SF3B1 Anticorps
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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Épitope
- AA 1-100
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SF3B1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human SAP155/SF3B1
- Isotype
- IgG
- Top Product
- Discover our top product SF3B1 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
- Autre désignation
- SAP155 (SF3B1 Produits)
- Synonymes
- anticorps Cus1, anticorps SAP145, anticorps SF3B145, anticorps SF3b1, anticorps SF3b150, anticorps Hsh155, anticorps MDS, anticorps PRP10, anticorps PRPF10, anticorps SAP155, anticorps SF3b155, anticorps 155kDa, anticorps 2810001M05Rik, anticorps AA409119, anticorps Prp10, anticorps TA-8, anticorps Targ4, anticorps hsh155, anticorps prp10, anticorps prpf10, anticorps sap155, anticorps SF3B1, anticorps Sap155, anticorps wu:fb99f09, anticorps splicing factor 3b subunit 2, anticorps splicing factor 3b subunit 1, anticorps splicing factor 3b, subunit 1, anticorps splicing factor 3b subunit 1 S homeolog, anticorps SF3B2, anticorps SF3B1, anticorps Sf3b1, anticorps sf3b1.S, anticorps sf3b1
- Sujet
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Synonyms: Hsh 155, MDS, Pre mRNA processing 10, Pre mRNA splicing factor SF3b 155 kDa subunit, PRP 10, PRP10, PRPF 10, PRPF10, SAP 155, SAP155, SF3B 1, SF3B 1, SF3b155, Spliceosome associated protein 155, Splicing factor 3b subunit 1 155 kDa, Splicing factor 3B subunit 1, SF3B1_HUMAN.
Background: SAP 155 is a 1,304 amino acid member of the SF3B1 family and contains eleven HEAT repeats. Localized to nuclear speckles and also to the cytoplasm during mitosis, SAP 155 is a subunit of the SF3B splicing factor. The SF3B splicing factor is a U2 snRNP-associated protein complex essential for spliceosome assembly. SF3B contains the spliceosomal proteins SAP 49, SAP 130, SAP 145 and SAP 155. Concomitant with splicing catalysis, SAP 155 is phosphorylated at its N-terminal Thr-Pro dipeptide motifs by Dyrk1A and cyclin E/Cdk2. This modification of SAP 155 is vital for a functional spliceosome as it is an essential event in the basic splicing reaction. Due to alternative splicing events, various SAP 155 isoforms are produced.
- ID gène
- 23451
- Pathways
- Chromatin Binding
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