FBXO45 anticorps (AA 110-210)

N° du produit ABIN1714025

Détail du produit anti-FBXO45 anticorps

Antigène: FBXO45 (F-Box Protein 45 (FBXO45))

Épitope: AA 110-210

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO45 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FBXO45

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur FBXO45

Antigène: FBXO45 (F-Box Protein 45 (FBXO45))

Autre désignation: FBXO45 (FBXO45 Produits)

Synonymes: anticorps Fbx45, anticorps 2610017J04Rik, anticorps AI463119, anticorps BC026799, anticorps zgc:65875, anticorps 3g27, anticorps F-box protein 45, anticorps F-box protein 45 S homeolog, anticorps FBXO45, anticorps fbxo45, anticorps Fbxo45, anticorps fbxo45.S

Sujet:

Synonyms: F box protein 45, F-box only protein 45, F-box/SPRY domain-containing protein 1, FBSP1_HUMAN, FBX45, fbxo45, hFbxo45.

Background: Belonging to the F-box family of proteins, FBXO45 is a 286 amino acid protein that contains one C-terminal F-box domain. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, including the cell cycle, the immune response, signaling cascades and developmental processes. They function by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IB- and -catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO45 can directly interact with Skp1 p19 and CUL-1. FBXO45 has been shown to be an estrogen-induced gene.

ID gène: 200933

UniProt: P0C2W1