TRRAP anticorps (AA 3401-3600)

N° du produit ABIN1714098

Cet anticorps anti-TRRAP Polyclonal Lapin (ABIN1714098) détecte spécifiquement TRRAP dans ICC, IHC (p), ELISA, IF (cc), IF (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Humain, Rat et Xenopus laevis.

Aperçu rapide pour TRRAP anticorps (AA 3401-3600) (ABIN1714098)

Antigène: TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))

Reactivité: Humain, Rat, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRRAP est non-conjugé

Application: Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TRRAP anticorps

Épitope: AA 3401-3600

Réactivité croisée: Humain, Rat, Xenopus laevis

Homologie: Mouse,Dog,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TRRAP

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur TRRAP

Antigène: TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))

Autre désignation: TRRAP

Sujet:

Synonyms: 350/400 kDa PCAF associated factor, FLJ10671, PAF 350/400, PAF 400, PAF350/400, PAF400, STAF 40, STAF40, TR AP, Tra 1, Tra1, Tra1 homolog, Transactivation / transformation domain associated protein, Transactivation/transformation domain associated protein, Transformation/transcription domain associated protein, TRAP, TRRAP_HUMAN.

Background: The transcription factors c-Myc and E2F are involved in regulating cell cycle progression. Overexpression of c-Myc in certain cell types induces noncycling cells to enter the cell cycle via a mechanism involving E2F-1 (1). E2F-1 is thought to regulate c-Myc expression via interactions with the retinoblastoma protein (2). TRRAP (for transformation/transcription domain-associated protein) interacts specifically with both c-Myc and E2F-1. Expression of trans-activated mutant TRRAP inhibits the oncogenic transformation of both c-Myc and E2F-1, suggesting that TRRAP is required for these oncogenic transcription factor pathways (3). TRRAP shares homology with the ATM/PI 3-kinase family, and it is highly conserved in evolution (4,5).

ID gène: 8295