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DOCK4 anticorps (AA 1001-1100)

DOCK4 Reactivité: Humain IF (p), ELISA, IF (cc), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1714146
  • Antigène Voir toutes DOCK4 Anticorps
    DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))
    Épitope
    • 14
    • 3
    • 3
    • 2
    • 1
    • 1
    AA 1001-1100
    Reactivité
    • 33
    • 10
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 29
    • 4
    Lapin
    Clonalité
    • 30
    • 3
    Polyclonal
    Conjugué
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DOCK4 est non-conjugé
    Application
    • 13
    • 12
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DOCK4
    Isotype
    IgG
    Top Product
    Discover our top product DOCK4 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))
    Autre désignation
    DOCK4 (DOCK4 Produits)
    Synonymes
    anticorps DOCK4, anticorps 5330406C03, anticorps 6330411N01Rik, anticorps AF263288, anticorps C030023J22, anticorps mKIAA0716, anticorps dedicator of cytokinesis 4, anticorps DOCK4, anticorps NAEGRDRAFT_81257, anticorps Dock4
    Sujet

    Synonyms: Dedicator of cytokinesis protein 4, Dock4, DOCK4_HUMAN, KIAA0716.

    Background: DOCK 4 is a cytoplasmic peripheral membrane protein that belongs to the DOCK family of cytokinesis-regulating proteins. Expressed ubiquitously with highest expression in prostate, ovary and skeletal muscle, DOCK 4 functions as a guanine nucleotide exchange factor (GEF) that activates the small GTPase Rap 1 and, via this activation, plays a role in the regulation of adherens junctions between cells. Similar to other DOCK family members, DOCK 4 contains an N-terminal SH3 domain, a C-terminal proline-rich region and two internal DOCK homology regions designated DHR1 and DHR2. Defects in the gene encoding DOCK 4 result in the inactivation of Rap 1 and are, thus, implicated in the pathogenesis of various cancers such as ovarian, prostate, glioma and colorectal carcinomas. Four isoforms of DOCK 4 are expressed due to alternative splicing events.

    ID gène
    9732
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