EYA1 anticorps

N° du produit ABIN1714156

Détail du produit anti-EYA1 anticorps

Antigène: EYA1 (Eyes Absent Homolog 1 (EYA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EYA1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EYA1

Isotype: IgG

Information d'application

Indications d'application: WB: (1:100-1000), IHC-P: (1:100-500), IF(IHC-P): (1:50-200)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur EYA1

Antigène: EYA1 (Eyes Absent Homolog 1 (EYA1))

Autre désignation: Eya1 (EYA1 Produits)

Synonymes: anticorps EYA1, anticorps bop, anticorps bor, anticorps XEya1, anticorps wu:fc13c10, anticorps zgc:100770, anticorps BOP, anticorps BOR, anticorps BOS1, anticorps EYA transcriptional coactivator and phosphatase 1, anticorps EYA transcriptional coactivator and phosphatase 1 L homeolog, anticorps EYA1, anticorps eya1, anticorps Eya1, anticorps eya1.L

Sujet:

Synonyms: BOP, BOR, Eya1, EYA1_HUMAN, eyes absent 1, eyes absent 1 homolog, eyes absent homolog 1 Drosophila, Eyes absent homolog 1, eyes absent homolog1, MGC141875.

Background: A gene on chromosome 8q13.3 encodes EYA1 (eyes absent), a protein with 16 exons. EYA1 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxyl terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serine-threonin)-rich amino terminal is highly divergent. EYA is expressed in flexor tendons and the developing central nervous system, kidney, eye and ear. EYA1 acts a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA1 plays a critical role in the development of the inner ear and kidney. EYA is involved in early inductive signaling, acting upstream of GDNF. EYA1 has been implicated in the autosomal dominant disorders branchio-oto-renal (BOR) syndrome and branhio-oto (BO) syndrome.

ID gène: 2138

Pathways: Sensory Perception of Sound, Positive Regulation of Response to DNA Damage Stimulus