DRAXIN anticorps (AA 251-349)
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- Antigène Voir toutes DRAXIN Anticorps
- DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
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Épitope
- AA 251-349
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DRAXIN est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human C1orf187
- Isotype
- IgG
- Top Product
- Discover our top product DRAXIN Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
- Autre désignation
- C1orf187 (DRAXIN Produits)
- Synonymes
- anticorps C1orf187, anticorps draxin, anticorps AGPA3119, anticorps UNQ3119, anticorps neucrin, anticorps 2610109H07Rik, anticorps MGC113312, anticorps dorsal inhibitory axon guidance protein, anticorps DRAXIN, anticorps Draxin, anticorps draxin
- Sujet
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Synonyms: AGPA3119, C1orf187, Chromosome 1 open reading frame 187, Dorsal inhibitory axon guidance protein, Dorsal repulsive axon guidance protein, DRAXI_HUMAN, Draxin, FLJ34999, MGC117222, Neucrin, OTTHUMP00000002262, UNQ3119.
Background: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.
- ID gène
- 374946
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