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G6PC2 anticorps (AA 31-130)

G6PC2 Reactivité: Humain ELISA, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1714378
  • Antigène Tous les produits G6PC2
    G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))
    Épitope
    • 5
    • 3
    • 2
    AA 31-130
    Reactivité
    • 19
    • 15
    • 15
    Humain
    Hôte
    • 22
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp G6PC2 est non-conjugé
    Application
    • 17
    • 6
    • 1
    • 1
    ELISA, Western Blotting (WB)
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat,Cow,Sheep,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))
    Autre désignation
    Glucose 6 phosphatase 2/IGRP (G6PC2 Produits)
    Synonymes
    anticorps IGRP, anticorps G6pc-rs, anticorps Igrp, anticorps g6pc2, anticorps igrp, anticorps glucose-6-phosphatase catalytic subunit 2, anticorps glucose-6-phosphatase, catalytic, 2, anticorps glucose-6-phosphatase, catalytic, 2 S homeolog, anticorps G6PC2, anticorps G6pc2, anticorps g6pc2.S
    Sujet

    Synonyms: G 6 Pase 2, G 6 Pase2, G6Pase 2, G6Pase2, G6PC 2, G6pc rs, G6pcrs, Glucose 6 phosphatase 2, Glucose 6 phosphatase, catalytic, 2, Glucose 6 phosphatase, catalytic, related, Glucose 6 phosphate catalytic 2, Islet specic G6CP related protein, Islet specic glucose 6 phosphatase, Islet specic glucose 6 phosphatase catalytic subunit related protein, G6PC2_HUMAN.

    Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-alpha, a second form, designated G6Pase-, contributes to blood glucose homeostasis in a wider range of tissues. Islet-specific G-6-Pase catalytic subunit-related protein (IGRP), a homolog of the catalytic subunit of G6Pase, may play a role in the regulation of islet metabolism and in insulin secretion induced by metabolites. The exact catalytic acivity of IGRP is not defined. Identification of inhibitors of IGRP have potential therapeutic benefits for treatment of type 2 diabetes resulting from insulin secretion defects. Structurally, IGRP has been shown to be a glycoprotein held in the endoplasmic reticulum by nine transmembrane domains, which are then degraded in cells through the proteasome pathway generating MHC class I presented peptides.

    ID gène
    57818
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