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MAML1 anticorps (AA 401-500)

MAML1 Reactivité: Poulet ELISA, WB, IHC (p), IHC (fro), ICC, IF (cc), IF (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1714470
  • Antigène Voir toutes MAML1 Anticorps
    MAML1 (Mastermind-Like 1 (MAML1))
    Épitope
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-500
    Reactivité
    • 30
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Poulet
    Hôte
    • 28
    • 1
    • 1
    Lapin
    Clonalité
    • 30
    Polyclonal
    Conjugué
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp MAML1 est non-conjugé
    Application
    • 24
    • 20
    • 13
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Poulet
    Homologie
    Human,Mouse,Rat,Dog,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human MAML1
    Isotype
    IgG
    Top Product
    Discover our top product MAML1 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Wu, Yu, Zhang, Zhang: "Cardioprotective effect of Notch signaling on the development of myocardial infarction complicated by diabetes mellitus." dans: Experimental and therapeutic medicine, Vol. 14, Issue 4, pp. 3447-3454, (2017) (PubMed).

  • Antigène
    MAML1 (Mastermind-Like 1 (MAML1))
    Autre désignation
    MAML1 (MAML1 Produits)
    Synonymes
    anticorps mam1, anticorps mam-1, anticorps xmam1, anticorps MAML1, anticorps AI644666, anticorps AW743257, anticorps D930008C07Rik, anticorps Mam-1, anticorps Mam1, anticorps mKIAA0200, anticorps mastermind like transcriptional coactivator 1 L homeolog, anticorps mastermind like transcriptional coactivator 1, anticorps mastermind like 1 (Drosophila), anticorps mastermind-like transcriptional coactivator 1, anticorps maml1.L, anticorps MAML1, anticorps Maml1
    Sujet

    Synonyms: Mam-1, Mam1, MAML 1, MAML 1, Maml1, MAML1_HUMAN, Mastermind like 1, Mastermind-like protein 1, mKIAA0200.

    Background: Notch receptors are involved in cell-fate determination in organisms as diverse as flies, frogs, and humans (1). The 'mastermind' gene has been identified in multiple genetic screens for modifiers of Notch mutations in Drosophila melanogaster (2). In Drosophila, loss-of-function mutations of Notch produce a 'neurogenic' phenotype in which cells destined to become epidermis switch fate and differentiate to neural cells (2). The human homolog, mastermind-like 1 (Mam1), localizes to nuclear bodies (2-4). Mam1 binds to the ankyrin repeat domain of all four mammalian Notch receptors, forms a DNA-binding complex with ICN and RBP-Jk, and amplifies Notch-induced transcription of Hes1 (2). Mam1 is an essential component of the transcriptional apparatus of Notch signaling (5). The gene which encodes Mam1 maps to human chromosome 5 (4).

    ID gène
    9794
    Pathways
    Signalisation Notch, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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