BAMBI anticorps (AA 101-200)
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- Antigène Voir toutes BAMBI Anticorps
- BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))
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Épitope
- AA 101-200
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Reactivité
- Humain, Rat, Souris, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BAMBI est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris, Porc, Rat
- Homologie
- Dog,Cow,Sheep,Rabbit,Guinea Pig
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human BAMBI
- Isotype
- IgG
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia." dans: Scientific reports, Vol. 6, pp. 27051, (2016) (PubMed).
: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." dans: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, (2016) (PubMed).
: "Identification and expression analyses of BAMBI mediated by FSH in swine luteinizing granulosa cells." dans: Theriogenology, Vol. 82, Issue 8, pp. 1094-101, (2014) (PubMed).
: "
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LPS/TLR4 Signaling Enhances TGF-β Response Through Downregulating BAMBI During Prostatic Hyperplasia." dans: Scientific reports, Vol. 6, pp. 27051, (2016) (PubMed).
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- Antigène
- BAMBI (BMP and Activin Membrane-Bound Inhibitor Homolog (BAMBI))
- Autre désignation
- BAMBI (BAMBI Produits)
- Sujet
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Synonyms: NMA, BMP and activin membrane-bound inhibitor homolog, Non-metastatic gene A protein, Putative transmembrane protein NMA, BAMBI
Background: BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. The BAMBI family of proteins are related to type I TGF-beta receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.
- ID gène
- 25805
- UniProt
- Q13145
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