ETF1 anticorps (AA 341-437)
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- Antigène Voir toutes ETF1 Anticorps
- ETF1 (Eukaryotic Translation Termination Factor 1 (ETF1))
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Épitope
- AA 341-437
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Reactivité
- Xenopus laevis, Poisson-ballons
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ETF1 est non-conjugé
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Application
- ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Poisson-ballons, Xenopus laevis
- Homologie
- Human,Mouse,Rat,Dog,Cow,Horse,Zebrafish,Arabidopsis Thaliana
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human eRF1
- Isotype
- IgG
- Top Product
- Discover our top product ETF1 Anticorps primaire
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- Indications d'application
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ETF1 (Eukaryotic Translation Termination Factor 1 (ETF1))
- Autre désignation
- eRF1 (ETF1 Produits)
- Synonymes
- anticorps D5S1995, anticorps ERF, anticorps ERF1, anticorps RF1, anticorps SUP45L1, anticorps TB3-1, anticorps AI463371, anticorps D6Ertd109e, anticorps eRF1, anticorps zeh0057, anticorps hm:zeh0057, anticorps wu:fa19e07, anticorps wu:fi31f01, anticorps cl1, anticorps RRF1, anticorps DDBDRAFT_0188023, anticorps DDBDRAFT_0191343, anticorps DDB_0188023, anticorps DDB_0191343, anticorps CG5605, anticorps Dm0184, anticorps Dmel\\CG5605, anticorps Group J, anticorps group J, anticorps l(3)00103, anticorps l(3)05637, anticorps l(3)77ABb, anticorps l(3)neo28, anticorps Eukaryotic release factor 1, anticorps eukaryotic translation termination factor 1, anticorps eukaryotic translation termination factor 1b, anticorps eukaryotic translation termination factor 1 S homeolog, anticorps eukaryotic peptide chain release factor subunit 1, anticorps eukaryotic petide chain release factor subunit 1, anticorps eukaryotic release factor 1, anticorps Eukaryotic peptide chain release factor subunit 1, anticorps ETF1, anticorps Etf1, anticorps etf1b, anticorps etf1, anticorps etf1.S, anticorps Tb11.22.0012, anticorps THAPSDRAFT_22240, anticorps TTHERM_00292170, anticorps LOC692937, anticorps erf1, anticorps eRF1, anticorps erfa-1
- Sujet
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Synonyms: Cl1 protein, D5S1995, ERF, eRF1, ERF1_HUMAN, ETF1, Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, Eukaryotic translation termination factor 1, MGC111066, Polypeptide chain release factor 1, Protein Cl1, RF1, Sup45 yeast omnipotent suppressor 45 homolog like 1, SUP45L1, TB3 1, TB3-1.
Background: Translation is carried out by the ribosome and several associated protein factors through three consecutive steps: initiation, elongation and termination. Termination of protein synthesis takes place when the ribosomal A site is occupied simultaneously by one of three stop codons and by a class 1 translation termination factor. In eukaryotes, this termination factor is the eukaryotic release factor 1 (eRF1), a protein that promotes hydrolysis of the last peptidyl-tRNA on the ribosome. eRF1 activity is stimulated by the association with the GTP-binding protein eRF3. eRF1 forms a quaternary complex with eRF3, GTP and the ribosome. This complex performs a dual role, where, in the GTP state,????????? it controls the positioning of eRF1 toward the stop codon and peptidyl-tRNA, and, in the GDP state,????????? it promotes the release of the eRFs from the ribosome. eRF1 contains a highly conserved Asn-Ile-Lys-Ser (NIKS) tetrapeptide, which is essential for the interaction of eRF1 with the ribosome. The gene encoding human eRF1 maps to chromosome 5q31.2.
- ID gène
- 2107
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