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GCAP1 anticorps (AA 51-150)

GUCA1A Reactivité: Souris, Rat ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1714544
  • Antigène Voir toutes GCAP1 (GUCA1A) Anticorps
    GCAP1 (GUCA1A) (Guanylate Cyclase Activator 1A (Retina) (GUCA1A))
    Épitope
    • 14
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    AA 51-150
    Reactivité
    • 21
    • 17
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 34
    • 1
    Lapin
    Clonalité
    • 34
    • 1
    Polyclonal
    Conjugué
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GCAP1 est non-conjugé
    Application
    • 29
    • 16
    • 12
    • 12
    • 10
    • 5
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GCAP1
    Isotype
    IgG
    Top Product
    Discover our top product GUCA1A Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    GCAP1 (GUCA1A) (Guanylate Cyclase Activator 1A (Retina) (GUCA1A))
    Autre désignation
    GCAP1 (GUCA1A Produits)
    Synonymes
    anticorps C6orf131, anticorps COD3, anticorps CORD14, anticorps GCAP, anticorps GCAP1, anticorps GUCA, anticorps GUCA1, anticorps dJ139D8.6, anticorps MGC84170, anticorps GUCA1A, anticorps guca1a, anticorps MGC146317, anticorps GC-A, anticorps Gcap1, anticorps Guca1, anticorps mGCAP1, anticorps gcap1, anticorps guanylate cyclase activator 1A, anticorps guanylate cyclase activator 1A L homeolog, anticorps guanylate cyclase activator 1A (retina), anticorps guanylate cyclase activator 1a (retina), anticorps GUCA1A, anticorps Guca1a, anticorps guca1a.L, anticorps guca1a
    Sujet

    Synonyms: COD3, GCAP 1, GCAP, Guanylate Cyclase Activating Protein Photoreceptor 1, Guanylate Cyclase Activating Protein Photoreceptor 1, Guanylate Cyclase Activator 1A, Guanylate Cyclase Activator 1A, Guanylin 1, Guanylin 1, guanylyl cyclase activating protein 1, Guanylyl cyclase-activating protein 1, GUC1A_HUMAN, GUCA, GUCA1, GUCA1A, GUCA1A.

    Background: intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-The binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of c-GMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90 % similar, consisting of 201 to 205 amino acids, and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event.

    ID gène
    2978
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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