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IGFBPL1 anticorps (AA 201-278)

IGFBPL1 Reactivité: Humain ELISA, IF (p), IF (cc), IHC (fro), IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1714840
  • Antigène Tous les produits IGFBPL1
    IGFBPL1 (Insulin-Like Growth Factor Binding Protein-Like 1 (IGFBPL1))
    Épitope
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-278
    Reactivité
    • 27
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 25
    • 3
    Lapin
    Clonalité
    • 28
    Polyclonal
    Conjugué
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IGFBPL1 est non-conjugé
    Application
    • 12
    • 12
    • 7
    • 5
    • 2
    • 2
    • 2
    ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human IGFBPL1
    Isotype
    IgG
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Liu, Zhang, He, Yang, Wang, Zhang, Guo: "Epigenetic silencing of IGFBPL1 promotes esophageal cancer growth by activating PI3K-AKT signaling." dans: Clinical epigenetics, Vol. 12, Issue 1, pp. 22, (2021) (PubMed).

  • Antigène
    IGFBPL1 (Insulin-Like Growth Factor Binding Protein-Like 1 (IGFBPL1))
    Autre désignation
    IGFBPL1 (IGFBPL1 Produits)
    Synonymes
    anticorps IGFBP-RP4, anticorps IGFBPRP4, anticorps bA113O24.1, anticorps 2810011G06Rik, anticorps 2810453O06Rik, anticorps IGFBPL, anticorps insulin like growth factor binding protein like 1, anticorps insulin-like growth factor binding protein-like 1, anticorps IGFBPL1, anticorps Igfbpl1
    Sujet

    Synonyms: bA113O24.1, IGFBP-related protein 10, IGFBP-RP4, IGFBPRP4, insulin-like growth factor binding protein related protein 4, insulin-like growth factor-binding protein-like 1, IBPL1_HUMAN, insulin-like growth factor-binding-related protein 4.

    Background: IGFBPL1 is a secreted IGF (Insulin-like growth factor) binding protein that is known to contain an Ig-like C2-type (immunoglobulin-like) domain, an IGFBP N-terminal domain and a Kazal-like domain. IGF-binding proteins characteristically act to extend the half-life of IGFs and may influence the growth promoting effects of the IGFs. The interaction of IGFBPs with IGFs can affect cell surface receptors, specifically, IGFBPs may enhance or decrease a cells insulin sensitivity. IGFBPL1 has been found to be down-regulated in multiple tumors and thus may be a likely tumor suppressor candidate. Highly expressed in both brain and testis, IGFBPL1 is found at lower levels in the prostate, bladder and lung.

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