STAT4 anticorps

N° du produit ABIN1714879

Détail du produit anti-STAT4 anticorps

Antigène: STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAT4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human STAT4

Isotype: IgG

Information d'application

Indications d'application: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C

Date de péremption: 12 months

Détails sur STAT4

Antigène: STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

Autre désignation: STAT4 (STAT4 Produits)

Sujet:

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011].

Synonyms: signal transducers and activators of transduction 4, CIS4, HSPC060, SOCS4, SOCS6, SSI4, STAI4, STAT 4, STAT4, STATI4, Suppressor of cytokine signaling 6, STAT4_HUMAN.

ID gène: 3665

Pathways: Signalistation JAK/STAT