C1ORF53 anticorps (AA 81-145)

N° du produit ABIN1714972

Détail du produit anti-C1ORF53 anticorps

Antigène: C1ORF53 (Chromosome 1 Open Reading Frame 53 (C1ORF53))

Épitope: AA 81-145

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1ORF53 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Réactivité croisée: Rat

Homologie: Human,Mouse,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human C1orf51

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-C1ORF53 (ABIN1714972)

Morgenstern, Peikert, Lübbert, Suppanz, Klemm, Alka, Steiert, Naumenko, Schendzielorz, Melchionda, Mühlhäuser, Knapp, Busch, Stiller, Dannenmaier, Lindau, Licheva, Eickhorst, Galbusera, Zerbes, Ryan et al.: "Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. ..." dans: Cell metabolism, Vol. 33, Issue 12, pp. 2464-2483.e18, (2022) (PubMed).

Détails sur C1ORF53

Antigène: C1ORF53 (Chromosome 1 Open Reading Frame 53 (C1ORF53))

Autre désignation: C1orf53 (C1ORF53 Produits)

Synonymes: anticorps chromosome 1 open reading frame 53, anticorps C1orf53

Sujet:

Synonyms: C1orf53, CA053_HUMAN, Chromosome 1 open reading frame 53, Hypothetical protein LOC388722, Uncharacterized protein C1orf53.

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf53 gene product has been provisionally designated C1orf53 pending further characterization.

ID gène: 388722