GMPPB anticorps (AA 111-210)

N° du produit ABIN1715025

Détail du produit anti-GMPPB anticorps

Antigène: GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))

Épitope: AA 111-210

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GMPPB est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GMPPB

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur GMPPB

Antigène: GMPPB (GDP-Mannose Pyrophosphorylase B (GMPPB))

Autre désignation: GMPPB (GMPPB Produits)

Synonymes: anticorps MDDGA14, anticorps MDDGB14, anticorps MDDGC14, anticorps AI317178, anticorps E430010H19, anticorps RGD1560458, anticorps gmppl, anticorps zgc:92026, anticorps GMPPB, anticorps gmppb, anticorps gmppb-a, anticorps gmppb-b, anticorps GDP-mannose pyrophosphorylase B, anticorps GDP-mannose pyrophosphorylase B L homeolog, anticorps GDP-mannose pyrophosphorylase B S homeolog, anticorps GMPPB, anticorps Gmppb, anticorps gmppb, anticorps LOAG_13550, anticorps gmppb.L, anticorps gmppb.S

Sujet:

Synonyms: GDP mannose pyrophosphorylase B, GDP-mannose pyrophosphorylase B, GMPPB, GMPPB_HUMAN, GTP-mannose-1-phosphate guanylyltransferase beta, KIAA1851, Mannose 1 phosphate guanylyltransferase, Mannose-1-phosphate guanyltransferase beta.

Background: GMPPB is a 360 amino acid protein that belongs to the transferase hexapeptide repeat family and is involved in protein modification pathways. Functioning as a GDP-mannose pyrophosphorylase, GMPPB enzymatically catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose and a free phosphate, a reaction that is involved in the production of N-linked oligosaccharides. Defects in the gene encoding GMPPB that cause errors in the glycosylation pathway may lead to congenital disorders of glycosylation (CDG). CDGs are multisystemic diseases that often involve both the central and peripheral nervous systems and are often characterized by endocrine and coagulation disorders. GMPPB is expressed as two isoforms due to alternative splicing events.

ID gène: 29925