VPREB1 anticorps (AA 61-145)

N° du produit ABIN1715058

Détail du produit anti-VPREB1 anticorps

Antigène: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Épitope: AA 61-145

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPREB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human VPREB1/CD179a

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur VPREB1

Antigène: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Autre désignation: VPREB1/CD179a (VPREB1 Produits)

Synonymes: anticorps IGI, anticorps IGVPB, anticorps VPREB, anticorps VpreB, anticorps CD179a, anticorps Vpreb-1, anticorps V-set pre-B cell surrogate light chain 1, anticorps immunoglobulin iota chain, anticorps immunoglobulin iota chain-like, anticorps pre-B lymphocyte 1, anticorps pre-B lymphocyte gene 1, anticorps VPREB1, anticorps LOC698810, anticorps LOC486411, anticorps Vpreb1

Sujet:

Synonyms: CD179 antigen like family member A, CD179 antigen-like family member A, CD179a, IGI, IGVPB, Immunoglobulin iota chain, Pre B lymphocyte 1, pre-B lymphocyte 1, Protein VPreB1, VpreB protein, VPREB 1, VPREB, VpreB protein, VPREB_HUMAN, VPREB1.

Background: VpreB is expressed in pre-B lymphocytes, but not in mature B cells or in other blood cell lineages. The gene which encodes VpreB maps to human chromosome 22q11.2. The VpreB and Lambda 5 genes encode the Iota and Omega polypeptide chains, respectively, which associate with the Ig-Mu chain to form a molecular complex that is expressed on the surface of pre-B cells. This complex presumably regulates Ig gene rearrangements in the early steps of B cell differentiation. In the mouse the two genes are simultaneously expressed in pre-B cells and belong to the same transcription unit. A primary transcript is synthesized from which the pre-B and Lambda 5 mRNAs are derived by alternative splicing. In the human, however, the two genes are separate and do not belong to the same transcription unit.

ID gène: 7441

Pathways: Production of Molecular Mediator of Immune Response, Regulation of Cell Size