CD81 anticorps
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- Antigène Voir toutes CD81 Anticorps
- CD81
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Reactivité
- Humain
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD81 est non-conjugé
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Application
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Specificité
- Anti-human CD81 (TAPA-1)
- Attributs du produit
- Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
- Purification
- Protein G
- Immunogène
- genetic immunisation with cDNA encoding human CD81
- Clone
- QV-6A8-S3
- Isotype
- IgG2b
- Top Product
- Discover our top product CD81 Anticorps primaire
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- Indications d'application
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Flow cytometry: 1.2 µg/10^6 cells
ELISA: 1:200 - 1:400
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Commentaires
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Synonyms: TAPA-1
- Restrictions
- For Research Use only
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- Buffer
- PBS, pH 7.2
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C
- Stockage commentaire
- short term: 2 °C - 8 °C, long term: -20 °C
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A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." dans: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).
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A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." dans: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).
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- Antigène
- CD81
- Autre désignation
- CD81 (CD81 Produits)
- Synonymes
- anticorps Tapa-1, anticorps Tapa1, anticorps Tspan28, anticorps CVID6, anticorps S5.7, anticorps TAPA1, anticorps TSPAN28, anticorps CD81 molecule, anticorps CD81 molecule b, anticorps CD81 antigen, anticorps Cd81 molecule, anticorps CD81, anticorps cd81b, anticorps Cd81
- Sujet
- CD81 (TAPA-1) belongs to the transmembrane 4 superfamily (tetraspanin family). CD81 is a widely expressed cell-surface protein that is characterized by the presence of four transmembranic domains, short N and C termini, a small extracellular loop (SEL) and a large extra-cellular loop (LEL). It is expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin and plays a role in the regulation of cell development, cell-growth and signal transduction. CD81 plays a critical role in Hepatitis C Infection and is involved in HCV entry due to its ability to interact with virus' E1/E2 glycoproteins. CD81 is an essential HCV host factor as silencing of CD81 expression by CD81-specific monoclonal antibodies in hepatoma cells inhibits HCV entry.
- UniProt
- P60033
- Pathways
- Inositol Metabolic Process, Hepatitis C
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