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NMDAR3A + 3B anticorps

GRIN3A/B Reactivité: Humain, Souris, Rat IP, WB, IHC Hôte: Souris Monoclonal K35-40 unconjugated
N° du produit ABIN1721533
  • Antigène Tous les produits NMDAR3A + 3B (GRIN3A/B)
    NMDAR3A + 3B (GRIN3A/B) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3A/B (GRIN3A/B))
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 2
    Souris
    Clonalité
    • 2
    Monoclonal
    Conjugué
    • 2
    Cet anticorp NMDAR3A + 3B est non-conjugé
    Application
    Immunoprecipitation (IP), Western Blotting (WB), Immunohistochemistry (IHC)
    Specificité
    Reacts with human Glutamate NMDA Receptor NR3A/B Subunit. Cross-reacts with mouse and rat protein. Do not cross-react with subunits NR1 or NR2A-D.
    Purification
    Purified (protein G)
    Immunogène
    Fusion protein of NR3A aa sequence 780-914 from the extracellular IIIIV loop.
    Clone
    K35-40
    Isotype
    IgG1
  • Indications d'application
    Working dilution: Optimal dilution should be determined by the end user.
    The following are guidelines only :
    IHC(1 - 10 μg/mL) WB (1 - 10 μg/mL)
    Restrictions
    For Research Use only
  • Buffer
    PBS, pH 7.4.
    Conseil sur la manipulation
    Dilute in PBS or medium that is identical to that used in the assay system.
    Stock
    -20 °C
    Stockage commentaire
    Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    NMDAR3A + 3B (GRIN3A/B) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 3A/B (GRIN3A/B))
    Abstract
    GRIN3A/B Produits
    Sujet
    Two new subunits of the NMDA subtype of glutamate receptor (NMDAR) have been identified, NR3A and NR3B, with NR3B likely being the final member of the NMDAR family. These subunits show high sequence homology, although different distribution patterns: NR3B is expressed predominately in motor neurons, while NR3A is more widely distributed. When expressed in Xenopus oocytes, NR3A or NR3B assemble with NR1 to form excitatory glycine receptors that are unaffected by glutatmate.

    Glutamate receptor ionotropic, NMDA 3A, GluN3A N-methyl-D-aspartate receptor subtype 3A, NMDAR3A, NR3A NMDAR-L
    ID gène
    116443
    UniProt
    Q8TCU5
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