FK506
Reactivité: Chemical
EIA
Hôte: Mouton
Polyclonal
unconjugated
Indications d'application
Working dilution: Optimal dilution should be determined by the end user.
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Dilute in PBS or medium which is identical to that used in the assay system.
Stock
-20 °C
Stockage commentaire
Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
Date de péremption
12 months
Antigène
Tacrolimus (FK506)
Autre désignation
FK-506
Classe de substances
Chemical
Sujet
FK-506 is a novel macrolide with similar, but more potent, immunosuppressant activity than cyclosporine. FK-506 is used for primary or rescue immunosuppression in patients after solid organ transplantation. Clinically relevant side effects of FK-506 administration are nephrotoxicity, neurotoxicity, diabetes mellitus, and hypertension. Most of these side effects are related to blood levels of FK-506 rather than dosage. Therefore, therapeutic drug monitoring of FK-506 is a prerequisite for therapy. The whole blood target level range aimed for in clinical practice is 3.0-20.0 ng/mL and depends on the patient's liver function, the nature of organ transplantation, and the time after transplantation.
Tacrolimus Fujimycin CAS : 109581-93-3 C44H69NO12 . H2O