ERK2 anticorps

N° du produit ABIN1724654

Détail du produit anti-ERK2 anticorps

Antigène: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ERK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Fonction: ERK2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human ERK2 expressed in E. Coli.

Clone: 4C11

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-ERK2 (ABIN1724654)

Whitehurst, Robinson, Moore, Cobb: "The death effector domain protein PEA-15 prevents nuclear entry of ERK2 by inhibiting required interactions." dans: The Journal of biological chemistry, Vol. 279, Issue 13, pp. 12840-7, (2004) (PubMed).

Hatano, Mori, Oh-hora, Kosugi, Fujikawa, Nakai, Niwa, Miyazaki, Hamaoka, Ogata: "Essential role for ERK2 mitogen-activated protein kinase in placental development." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 8, Issue 11, pp. 847-56, (2003) (PubMed).

Détails sur ERK2

Antigène: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Autre désignation: ERK2 (MAPK1 Produits)

Synonymes: anticorps ERK-1, anticorps ERK1, anticorps ERT2, anticorps HS44KDAP, anticorps HUMKER1A, anticorps P44ERK1, anticorps P44MAPK, anticorps PRKM3, anticorps p44-ERK1, anticorps p44-MAPK, anticorps Erk-1, anticorps Erk1, anticorps Ert2, anticorps Esrk1, anticorps Mnk1, anticorps Mtap2k, anticorps Prkm3, anticorps p44, anticorps p44erk1, anticorps p44mapk, anticorps ERK, anticorps ERK2, anticorps ERT1, anticorps MAPK2, anticorps P42MAPK, anticorps PRKM1, anticorps PRKM2, anticorps p38, anticorps p40, anticorps p41, anticorps p41mapk, anticorps 9030612K14Rik, anticorps AA407128, anticorps AU018647, anticorps C78273, anticorps Erk2, anticorps Prkm1, anticorps p42mapk, anticorps zERK2, anticorps MAPK1, anticorps Xp42, anticorps erk, anticorps erk2, anticorps ert1, anticorps mapk, anticorps mapk1b, anticorps mapk2, anticorps mpk1, anticorps prkm1, anticorps prkm2, anticorps mapk1, anticorps mapk1a, anticorps xp42, anticorps ATMPK1, anticorps F14N23.9, anticorps F14N23_9, anticorps MITOGEN-ACTIVATED PROTEIN KINASE, anticorps mitogen-activated protein kinase 1, anticorps MNK1, anticorps ATMPK2, anticorps MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2, anticorps T30E16.13, anticorps T30E16_13, anticorps mitogen-activated protein kinase homolog 2, anticorps mitogen-activated protein kinase 3, anticorps mitogen-activated protein kinase 1, anticorps mitogen activated protein kinase 1, anticorps mitogen-activated protein kinase 1 L homeolog, anticorps mitogen-activated protein kinase 1 S homeolog, anticorps mitogen activated protein kinase 3, anticorps mitogen-activated protein kinase homolog 2, anticorps MAPK3, anticorps Mapk3, anticorps MAPK1, anticorps Mapk1, anticorps mapk1, anticorps mapk1.L, anticorps mapk1.S, anticorps PfMAP1, anticorps MPK1, anticorps PVX_084965, anticorps LOC9328617, anticorps Tsp_01601, anticorps MPK2

Sujet:

Description: ERK2 (also designated extracellular-signal-related kinase 2 or mitogen-activated protein kinase 1), with 360-amino acid protein (about 40 kDa), belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of ERK2 requires its phosphorylation by upstream kinases. ERK2 is located in the cytoplasm of resting cells and translocates into the nucleus upon extracellular stimuli by active transport of a dimer. ERK2 is essential for placental development and ERK2 in the trophoblast compartment may be indispensable for the vascularization of the labyrinth.

Aliases: ERK, p38, p40, p41, ERT1, MAPK2, PRKM1, P42MAPK, p41mapk, MAPK1

Poids moléculaire: 41kDa

ID gène: 5594

HGNC: 5594

UniProt: P28482

Pathways: Signalisation MAPK, Signalisation RTK, Apoptose, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins