RPS6KA1 anticorps

N° du produit ABIN1724669

Détail du produit anti-RPS6KA1 anticorps

Antigène: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RPS6KA1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Fonction: RSK1 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human RSK1 expressed in E. Coli.

Clone: 10B1D7A9

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur RPS6KA1

Antigène: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Autre désignation: RSK1 (RPS6KA1 Produits)

Synonymes: anticorps HU-1, anticorps MAPKAPK1A, anticorps RSK, anticorps RSK1, anticorps Rsk1, anticorps p90rsk, anticorps rsk, anticorps RPS6KA, anticorps hu-1, anticorps mapkapk1a, anticorps rsk1, anticorps wu:fc56h07, anticorps zgc:152654, anticorps ribosomal protein S6 kinase A1, anticorps ribosomal protein S6 kinase polypeptide 1, anticorps ribosomal protein S6 kinase A1-like, anticorps ribosomal protein S6 kinase A1 L homeolog, anticorps ribosomal protein S6 kinase a, polypeptide 1, anticorps RPS6KA1, anticorps Rps6ka1, anticorps RPS6KA1L, anticorps rps6ka1.L, anticorps rps6ka1

Sujet:

Description: Rsk1 is a member of a family of 90 kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB. RSK proteins possess two separate kinase domains, the C terminal kinase domain and the N terminal kinase domain, separated by a linker region containing a hydrophobic motif. RSK is activated by many stimuli including growth factors, phorbol esters, cAMP, heat shock, and irradiation.

Aliases: RSK, HU-1, RSK1, MAPKAPK1A, RPS6KA1

ID gène: 6195

HGNC: 6195

UniProt: Q15418

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades