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KAT5 anticorps

KAT5 Reactivité: Humain ELISA, IHC Hôte: Souris Monoclonal 3F9 unconjugated
N° du produit ABIN1724672
  • Antigène Voir toutes KAT5 Anticorps
    KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
    Reactivité
    • 84
    • 64
    • 55
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 101
    • 13
    Souris
    Clonalité
    • 102
    • 13
    Monoclonal
    Conjugué
    • 56
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp KAT5 est non-conjugé
    Application
    • 85
    • 52
    • 27
    • 27
    • 22
    • 17
    • 9
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Fonction
    TIP60 Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human TIP60 expressed in E. Coli.
    Clone
    3F9
    Isotype
    IgG2b
    Top Product
    Discover our top product KAT5 Anticorps primaire
  • Indications d'application
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Raisner, Madhani: "Patterning chromatin: form and function for H2A.Z variant nucleosomes." dans: Current opinion in genetics & development, Vol. 16, Issue 2, pp. 119-24, (2006) (PubMed).

    Jin, Cai, Li, Conaway, Workman, Conaway, Kusch: "In and out: histone variant exchange in chromatin." dans: Trends in biochemical sciences, Vol. 30, Issue 12, pp. 680-7, (2005) (PubMed).

  • Antigène
    KAT5 (K(lysine) Acetyltransferase 5 (KAT5))
    Autre désignation
    TIP60 (KAT5 Produits)
    Sujet

    Description: HTATIP (HIV-1 Tat interacting protein TIP60, about 60 kDa) belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. In addition to the growing number of post-translational histone modifications regulating chromatin structure, cells can also exchange canonical histones with variant histones that can directly or indirectly modulate chromatin structure. There are five major variants of histone H2A: canonical H2A (most abundant), H2A.X, MacroH2A, H2ABbd and H2A.Z. Histone H2A.Z, the most conserved variant across species, functions as both a positive and negative regulator of transcription and is important for chromosome stability. Several homologous protein complexes, such as SWR-C, TIP60 and SRCAP (mammals), have been shown to catalyze the ATP-dependent exchange of H2A.Z for H2A in the nucleosome. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.

    Aliases: TIP60 (HTATIP)

    Poids moléculaire
    60kDa
    ID gène
    10524
    HGNC
    10524
    UniProt
    Q92993
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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