Survivin anticorps

N° du produit ABIN1724686

Détail du produit anti-Survivin anticorps

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Survivin est non-conjugé

Application: ELISA

Fonction: Survivin Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of Survivin expressed in E. Coli.

Clone: 2H5H2

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Survivin (ABIN1724686)

Karam, Lotan, Ashfaq, Sagalowsky, Shariat: "Survivin expression in patients with non-muscle-invasive urothelial cell carcinoma of the bladder." dans: Urology, Vol. 70, Issue 3, pp. 482-6, (2007) (PubMed).

Piras, Murtas, Minerba, Ugalde, Floris, Maxia, Colombari, Perra, Sirigu: "Nuclear survivin is associated with disease recurrence and poor survival in patients with cutaneous malignant melanoma." dans: Histopathology, Vol. 50, Issue 7, pp. 835-42, (2007) (PubMed).

Détails sur Survivin

Antigène: Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Autre désignation: Survivin (BIRC5 Produits)

Synonymes: anticorps AP14, anticorps API4, anticorps EPR-1, anticorps AAC-11, anticorps Api4, anticorps TIAP, anticorps survivin40, anticorps bir5a, anticorps survivin, anticorps BIR1, anticorps Su2, anticorps XBIR1, anticorps XSurvivin1, anticorps Xsvv1, anticorps api4, anticorps bir1-A, anticorps epr-1, anticorps svv1, anticorps xSurvivin, anticorps xsurv, anticorps Su1, anticorps birc5.2, anticorps svv2, anticorps xSurvivin2, anticorps bir5b, anticorps SIX, anticorps birc5.2-a, anticorps birc5.2-b, anticorps baculoviral IAP repeat containing 5, anticorps baculoviral IAP repeat-containing 5, anticorps baculoviral IAP repeat containing 5a, anticorps baculoviral IAP repeat-containing 5, gene 1 L homeolog, anticorps baculoviral IAP repeat containing 5 L homeolog, anticorps baculoviral IAP repeat containing 5b, anticorps baculoviral IAP repeat containing 5 S homeolog, anticorps BIRC5, anticorps Birc5, anticorps birc5a, anticorps birc5.1.L, anticorps birc5.2.L, anticorps birc5b, anticorps birc5.2.S

Sujet:

Description: Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

Aliases: API4, EPR-1, BIRC5

ID gène: 332

HGNC: 332

UniProt: O15392

Pathways: Apoptose, Cycle Cellulaire, Nuclear Hormone Receptor Binding