EPH Receptor B2 anticorps (AA 17-200)

N° du produit ABIN1724695

Détail du produit anti-EPH Receptor B2 anticorps

Antigène: EPH Receptor B2 (EPHB2)

Épitope: AA 17-200

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPH Receptor B2 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC)

Fonction: EphB2 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of EphB2 (aa17-200) expressed in E. Coli.

Clone: 2D12C6

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-EPH Receptor B2 (ABIN1724695)

Diehl, Bruno, Wilkinson, Loose, Wilting, Schweigerer, Klein: "Altered expression patterns of EphrinB2 and EphB2 in human umbilical vessels and congenital venous malformations." dans: Pediatric research, Vol. 57, Issue 4, pp. 537-44, (2005) (PubMed).

Huusko, Ponciano-Jackson, Wolf, Kiefer, Azorsa, Tuzmen, Weaver, Robbins, Moses, Allinen, Hautaniemi, Chen, Elkahloun, Basik, Bova, Bubendorf, Lugli, Sauter, Schleutker, Ozcelik, Elowe, Pawson, Trent et al.: "Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer. ..." dans: Nature genetics, Vol. 36, Issue 9, pp. 979-83, (2004) (PubMed).

Détails sur EPH Receptor B2

Antigène: EPH Receptor B2 (EPHB2)

Autre désignation: EphB2 (EPHB2 Produits)

Sujet:

Description: EphB2: EPH receptor B2. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.

Aliases: DRT, ERK, CAPB, Hek5

ID gène: 2048

HGNC: 2048

UniProt: P29323

Pathways: Signalisation RTK, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins