EPH Receptor B4 anticorps (AA 562-612)

N° du produit ABIN1724713

Détail du produit anti-EPH Receptor B4 anticorps

Antigène: EPH Receptor B4 (EPHB4)

Épitope: AA 562-612

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EPH Receptor B4 est non-conjugé

Application: ELISA

Fonction: EphB4 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of EphB4 (aa562-612)expressed in E. Coli.

Clone: 7H4A6

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-EPH Receptor B4 (ABIN1724713)

Red-Horse, Kapidzic, Zhou, Feng, Singh, Fisher: "EPHB4 regulates chemokine-evoked trophoblast responses: a mechanism for incorporating the human placenta into the maternal circulation." dans: Development (Cambridge, England), Vol. 132, Issue 18, pp. 4097-106, (2005) (PubMed).

Xia, Kumar, Masood, Zhu, Reddy, Krasnoperov, Quinn, Henshall, Sutherland, Pinski, Daneshmand, Buscarini, Stein, Zhong, Broek, Roy-Burman, Gill: "EphB4 expression and biological significance in prostate cancer." dans: Cancer research, Vol. 65, Issue 11, pp. 4623-32, (2005) (PubMed).

Jiménez-Vega, Yepiz-Plascencia, Söderhäll, Vargas-Albores: "A single WAP domain-containing protein from Litopenaeus vannamei hemocytes." dans: Biochemical and biophysical research communications, Vol. 314, Issue 3, pp. 681-7, (2004) (PubMed).

Détails sur EPH Receptor B4

Antigène: EPH Receptor B4 (EPHB4)

Autre désignation: EphB4 (EPHB4 Produits)

Sujet:

Description: EphB4: EPH receptor B4. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

Aliases: HTK, MYK1, TYRO11

Poids moléculaire: 108kDa

ID gène: 2050

HGNC: 2050

UniProt: P54760

Pathways: Signalisation RTK