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HSC70 Interacting Protein HIP anticorps

ST13 Reactivité: Humain WB, ELISA, IHC, ICC Hôte: Souris Monoclonal 3B10 unconjugated
N° du produit ABIN1724716
  • Antigène Voir toutes HSC70 Interacting Protein HIP (ST13) Anticorps
    HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
    Reactivité
    • 43
    • 15
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 35
    • 9
    Souris
    Clonalité
    • 36
    • 8
    Monoclonal
    Conjugué
    • 25
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HSC70 Interacting Protein HIP est non-conjugé
    Application
    • 43
    • 16
    • 13
    • 13
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Fonction
    ST13 Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human ST13 expressed in E. Coli.
    Clone
    3B10
    Isotype
    IgG1
  • Indications d'application

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Zhou, Lucas, Chan, Issaq, Petricoin, Liotta, Veenstra, Conrads: "An investigation into the human serum "interactome"." dans: Electrophoresis, Vol. 25, Issue 9, pp. 1289-98, (2004) (PubMed).

  • Antigène
    HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))
    Autre désignation
    ST13 (ST13 Produits)
    Synonymes
    anticorps CG32789, anticorps Dmel\\CG32789, anticorps anon-EST:fe1A9, anticorps 1110007I03Rik, anticorps 3110002K08Rik, anticorps AW555194, anticorps HIP, anticorps HOP, anticorps HSPABP, anticorps HSPABP1, anticorps PRO0786, anticorps SNC6, anticorps p48, anticorps AAG2, anticorps FAM10A1, anticorps FAM10A4, anticorps P48, anticorps Hsc/Hsp70-interacting protein, anticorps suppression of tumorigenicity 13, anticorps ST13, Hsp70 interacting protein, anticorps suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein), anticorps HIP, anticorps St13, anticorps ST13
    Sujet

    Description: ST13 (suppression of tumorigenicity protein 13), also known as Hip (HSP70-interacting protein), is one of several co-chaperones that regulate activities of the HSP70 chaperone family. The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family. By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.

    Aliases: HIP, HOP, P48, AAG2, SNC6, HSPABP, FAM10A1, FAM10A4, HSPABP1, ST13

    Poids moléculaire
    48kDa
    ID gène
    6767
    HGNC
    6767
    UniProt
    P50502
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