CD247 anticorps
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- Antigène Voir toutes CD247 Anticorps
- CD247 (CD247 Molecule (CD247))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD247 est non-conjugé
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Application
- ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- Fonction
- CD247 Antibody
- Purification
- Ascitic fluid
- Immunogène
- Purified recombinant fragment of human CD247 expressed in E. Coli.
- Clone
- 4B10
- Isotype
- IgG1
- Top Product
- Discover our top product CD247 Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." dans: Nature methods, Vol. 2, Issue 8, pp. 591-8, (2005) (PubMed).
: "Reconstitution of deficient T cell receptor zeta chain restores T cell signaling and augments T cell receptor/CD3-induced interleukin-2 production in patients with systemic lupus erythematosus." dans: Arthritis and rheumatism, Vol. 48, Issue 7, pp. 1948-55, (2003) (PubMed).
: "TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 4, pp. 1705-12, (2002) (PubMed).
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Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." dans: Nature methods, Vol. 2, Issue 8, pp. 591-8, (2005) (PubMed).
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- Antigène
- CD247 (CD247 Molecule (CD247))
- Autre désignation
- CD247 (CD247 Produits)
- Synonymes
- anticorps CD3-ZETA, anticorps CD3H, anticorps CD3Q, anticorps CD3Z, anticorps T3Z, anticorps TCRZ, anticorps 4930549J05Rik, anticorps A430104F18Rik, anticorps AW552088, anticorps Cd3, anticorps Cd3-eta, anticorps Cd3-zeta, anticorps Cd3h, anticorps Cd3z, anticorps Cd3zeta, anticorps T3z, anticorps Tcrk, anticorps Tcrz, anticorps LOC100136514, anticorps LOC100136549, anticorps LOC100305023, anticorps CD247, anticorps TCRzeta, anticorps CD247 molecule, anticorps CD247 antigen, anticorps CD3zeta-2, anticorps CD3zeta-1, anticorps Cd247 molecule, anticorps CD247, anticorps Cd247, anticorps cd3z, anticorps cd247
- Sujet
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Description: The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Aliases: T3Z, CD3H, CD3Q, CD3Z, TCRZ, CD3-ZETA, CD247
- Poids moléculaire
- 18kDa
- ID gène
- 919
- HGNC
- 919
- UniProt
- P20963
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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