RUNX3 anticorps (AA 186-252)

N° du produit ABIN1724742

Détail du produit anti-RUNX3 anticorps

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Épitope: AA 186-252

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RUNX3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Fonction: RUNX3 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human RUNX3 (AA:186-252) expressed in E. Coli.

Clone: 2B3

Isotype: IgG2b

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-RUNX3 (ABIN1724742)

Mei, Bai, Liu, Li, Wu, Yu, Zheng: "RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration." dans: Journal of cancer research and clinical oncology, Vol. 137, Issue 12, pp. 1823-30, (2011) (PubMed).

Détails sur RUNX3

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Autre désignation: RUNX3 (RUNX3 Produits)

Synonymes: anticorps runxb, anticorps RUNX3, anticorps CBFA3, anticorps frrunx3, anticorps runx3, anticorps aml2, anticorps cbfa3, anticorps pebp2ac, anticorps AML2, anticorps Cbfa3, anticorps Pebp2a3, anticorps PEBP2aC, anticorps runt-related transcription factor 3, anticorps runt related transcription factor 3, anticorps runt related transcription factor 3 L homeolog, anticorps runx3, anticorps RUNX3, anticorps runx3.L, anticorps Runx3

Sujet:

Description: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Aliases: AML2, CBFA3, PEBP2aC, FLJ34510, MGC16070

Poids moléculaire: 44.4kDa

ID gène: 864

HGNC: 864

UniProt: Q13761