Dynactin 4 anticorps (AA 57-298)

N° du produit ABIN1724791

Détail du produit anti-Dynactin 4 anticorps

Antigène: Dynactin 4 (DCTN4)

Épitope: AA 57-298

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Dynactin 4 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Fonction: DCTN4 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human DCTN4 (AA: 57-298) expressed in E. Coli.

Clone: 3G9D7

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Dynactin 4 (ABIN1724791)

Ayalon, Davis, Scotland, Bennett: "An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan." dans: Cell, Vol. 135, Issue 7, pp. 1189-200, (2008) (PubMed).

Lim, Cater, Mercer, La Fontaine: "Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A." dans: The Journal of biological chemistry, Vol. 281, Issue 20, pp. 14006-14, (2006) (PubMed).

Détails sur Dynactin 4

Antigène: Dynactin 4 (DCTN4)

Autre désignation: DCTN4 (DCTN4 Produits)

Synonymes: anticorps DYN4, anticorps P62, anticorps MGC84654, anticorps zgc:112431, anticorps MGC97564, anticorps 1110001K06Rik, anticorps 4930547K17Rik, anticorps C130039E17Rik, anticorps p62, anticorps dynactin subunit 4, anticorps dynactin subunit 4 L homeolog, anticorps dynactin 4, anticorps dynactin 4, putative, anticorps DCTN4, anticorps Dctn4, anticorps dctn4.L, anticorps dctn4, anticorps PKH_031720

Sujet:

Description: Dynactin 4 could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.The dynactin complex binds cargo, such as vesicles and organelles, to cytoplasmic dynein for retrograde microtubule-mediated trafficking and could feasibly be involved in the copper-regulated trafficking of ATP7B.

Aliases: P62, DYN4

Poids moléculaire: 52.3kDa

ID gène: 51164

HGNC: 51164

UniProt: Q9UJW0