Integrin beta 4 anticorps (AA 1619-1822)

N° du produit ABIN1724805

Détail du produit anti-Integrin beta 4 anticorps

Antigène: Integrin beta 4 (ITGB4)

Épitope: AA 1619-1822

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Purification: purified

Immunogène: Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. coli.

Clone: 10B10D5

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-Integrin beta 4 (ABIN1724805)

Liu, Qin, Liu, Xiang: "Downregulation of integrin β4 decreases the ability of airway epithelial cells to present antigens." dans: PLoS ONE, Vol. 7, Issue 4, pp. e32060, (2012) (PubMed).

Détails sur Integrin beta 4

Antigène: Integrin beta 4 (ITGB4)

Autre désignation: ITGB4 (ITGB4 Produits)

Synonymes: anticorps AA407042, anticorps C230078O20, anticorps CD104, anticorps integrin subunit beta 4, anticorps integrin beta 4, anticorps ITGB4, anticorps Itgb4

Sujet:

Description: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. , , ,

Aliases: CD104

Poids moléculaire: 202 kDa

ID gène: 3691

HGNC: 3691

Pathways: Integrin Complex