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TP53BP1 anticorps (AA 574-773)

TP53BP1 Reactivité: Humain WB, IHC, ELISA, FACS Hôte: Souris Monoclonal 6B3E10 unconjugated
N° du produit ABIN1724820
  • Antigène Voir toutes TP53BP1 Anticorps
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    Épitope
    • 32
    • 21
    • 15
    • 11
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 574-773
    Reactivité
    • 104
    • 63
    • 61
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 108
    • 8
    • 2
    • 1
    Souris
    Clonalité
    • 102
    • 17
    Monoclonal
    Conjugué
    • 58
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp TP53BP1 est non-conjugé
    Application
    • 44
    • 29
    • 27
    • 27
    • 25
    • 18
    • 17
    • 12
    • 10
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    Fonction
    TP53BP1 Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human TP53BP1 (AA: 574-773) expressed in E. Coli.
    Clone
    6B3E10
    Isotype
    IgG1
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Nakada, Yonamine, Matsuo: "RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1." dans: Cancer research, Vol. 72, Issue 19, pp. 4974-83, (2012) (PubMed).

    Mok, Henderson: "The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci." dans: The international journal of biochemistry & cell biology, Vol. 44, Issue 9, pp. 1398-409, (2012) (PubMed).

  • Antigène
    TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
    Autre désignation
    TP53BP1 (TP53BP1 Produits)
    Synonymes
    anticorps TP53BP1, anticorps MGC160112, anticorps 53BP1, anticorps Tp53bp1, anticorps m53BP1, anticorps p202, anticorps Trp53bp1, anticorps tumor protein p53 binding protein 1, anticorps tumor suppressor p53-binding protein 1, anticorps tumor protein p53 binding protein 1 (predicted), 5 prime, anticorps transformation related protein 53 binding protein 1, anticorps TP53BP1, anticorps tp53bp1, anticorps LOC100550605, anticorps Trp53bp1, anticorps Tp53bp1
    Sujet

    Description: T protein p53 binding protein 1 may have a role in checkpoint signaling during mitosis,enhance TP53-mediated transcriptional activation and play a role in the response to DNA damage.

    Aliases: p202, 53BP1

    Poids moléculaire
    213.6kDa
    ID gène
    7158
    HGNC
    7158
    UniProt
    Q12888
    Pathways
    Réparation de l'ADN
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