Integrin Alpha2b anticorps (AA 45-149)
(2 références)-
- Antigène Voir toutes Integrin Alpha2b (CD41) Anticorps
- Integrin Alpha2b (CD41)
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Épitope
- AA 45-149
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Integrin Alpha2b est non-conjugé
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Application
- Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
- Fonction
- ITGA2B Antibody
- Purification
- Ascitic fluid
- Immunogène
- Purified recombinant fragment of human ITGA2B (AA: 45-149) expressed in E. Coli.
- Clone
- 2E10C9
- Isotype
- IgG1
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anti-Integrin Alpha2b (CD41) (AA 351-450) antibody
CD41 Reactivité: Humain, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Hôte: Lapin Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivité: Souris FACS, ELISA, IHC (fro), IP, IHC (p) Hôte: Rat Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivité: Souris FACS, ELISA, IHC (fro), IP, IHC (p), Func Hôte: Rat Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivité: Humain, Non-Human Primate FACS, IHC (fro) Hôte: Souris Monoclonal HIP2 unconjugated
anti-Integrin Alpha2b (CD41) antibody (Biotin)CD41 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-06 Biotin
anti-Integrin Alpha2b (CD41) antibody (FITC)CD41 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-06 FITC
anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibodyCD41 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reactivité: Humain, Non-Human Primate FACS, IHC (fro) Hôte: Souris Monoclonal HIP8 unconjugated
anti-Integrin Alpha2b (CD41) antibody (PE)CD41 Reactivité: Souris FACS Hôte: Rat Monoclonal MWReg30 PE
anti-Integrin Alpha2b (CD41) (AA 639-887) antibodyCD41 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia." dans: Pediatric blood & cancer, Vol. 59, Issue 2, pp. 335-8, (2012) (PubMed).
: "Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models." dans: Blood, Vol. 118, Issue 23, pp. 5996-6005, (2011) (PubMed).
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: "Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia." dans: Pediatric blood & cancer, Vol. 59, Issue 2, pp. 335-8, (2012) (PubMed).
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- Antigène
- Integrin Alpha2b (CD41)
- Autre désignation
- ITGA2B (CD41 Produits)
- Sujet
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Description: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Aliases: GT, GTA, CD41, GP2B, HPA3, CD41B, GPIIb, BDPLT2
- Poids moléculaire
- 113.4kDa
- ID gène
- 3674
- HGNC
- 3674
- UniProt
- P08514
- Pathways
- Integrin Complex
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