Integrin Alpha2b anticorps (AA 45-149)
-
- Antigène Voir toutes Integrin Alpha2b (CD41) Anticorps
- Integrin Alpha2b (CD41)
-
Épitope
- AA 45-149
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp Integrin Alpha2b est non-conjugé
-
Application
- Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
- Fonction
- ITGA2B Antibody
- Purification
- Ascitic fluid
- Immunogène
- Purified recombinant fragment of human ITGA2B (AA: 45-149) expressed in E. Coli.
- Clone
- 2E10C9
- Isotype
- IgG1
-
-
- Indications d'application
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia." dans: Pediatric blood & cancer, Vol. 59, Issue 2, pp. 335-8, (2012) (PubMed).
: "Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models." dans: Blood, Vol. 118, Issue 23, pp. 5996-6005, (2011) (PubMed).
: "
-
Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia." dans: Pediatric blood & cancer, Vol. 59, Issue 2, pp. 335-8, (2012) (PubMed).
-
- Antigène
- Integrin Alpha2b (CD41)
- Autre désignation
- ITGA2B (CD41 Produits)
- Synonymes
- anticorps AI172977, anticorps CD41, anticorps CD41B, anticorps GpIIb, anticorps alphaIIb, anticorps BDPLT16, anticorps BDPLT2, anticorps GP2B, anticorps GPIIb, anticorps GT, anticorps GTA, anticorps HPA3, anticorps integrin alpha 2b, anticorps integrin subunit alpha 2b, anticorps Itga2b, anticorps ITGA2B
- Sujet
-
Description: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Aliases: GT, GTA, CD41, GP2B, HPA3, CD41B, GPIIb, BDPLT2
- Poids moléculaire
- 113.4kDa
- ID gène
- 3674
- HGNC
- 3674
- UniProt
- P08514
- Pathways
- Integrin Complex
-