KLF1 anticorps (AA 208-362)

N° du produit ABIN1724828

Détail du produit anti-KLF1 anticorps

Antigène: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Épitope: AA 208-362

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KLF1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Fonction: KLF1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human KLF1 (AA: 208-362) expressed in E. Coli.

Clone: 1B6A3

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-KLF1 (ABIN1724828)

Alhashem, Vinjamur, Basu, Klingmüller, Gaensler, Lloyd: "Transcription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter binding." dans: The Journal of biological chemistry, Vol. 286, Issue 28, pp. 24819-27, (2011) (PubMed).

Zhou, Liu, Sun, Pawlik, Townes: "KLF1 regulates BCL11A expression and gamma- to beta-globin gene switching." dans: Nature genetics, Vol. 42, Issue 9, pp. 742-4, (2010) (PubMed).

Détails sur KLF1

Antigène: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Autre désignation: KLF1 (KLF1 Produits)

Synonymes: anticorps KLF1, anticorps EKLF, anticorps HBFQTL6, anticorps INLU, anticorps Eklf, anticorps Nan, anticorps Kruppel-like factor 1 (erythroid), anticorps Kruppel like factor 1, anticorps KLF-4, anticorps KLF1, anticorps Klf1

Sujet:

Description: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.

Aliases: EKLF, INLU, HBFQTL6

Poids moléculaire: 38.2kDa

ID gène: 10661

HGNC: 10661

UniProt: Q13351