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FGF4 anticorps (AA 62-123)

FGF4 Reactivité: Humain ELISA Hôte: Souris Monoclonal 2D7D5 unconjugated
N° du produit ABIN1724833
  • Antigène Voir toutes FGF4 Anticorps
    FGF4 (Fibroblast Growth Factor 4 (FGF4))
    Épitope
    • 15
    • 12
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 62-123
    Reactivité
    • 64
    • 23
    • 13
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 61
    • 5
    • 1
    • 1
    Souris
    Clonalité
    • 62
    • 6
    Monoclonal
    Conjugué
    • 30
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp FGF4 est non-conjugé
    Application
    • 30
    • 27
    • 21
    • 13
    • 13
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA
    Fonction
    FGF4 Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human FGF4 (AA: 62-123) expressed in E. Coli.
    Clone
    2D7D5
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Johannesson, Ståhlberg, Ameri, Sand, Norrman, Semb: "FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner." dans: PLoS ONE, Vol. 4, Issue 3, pp. e4794, (2009) (PubMed).

    Mayshar, Rom, Chumakov, Kronman, Yayon, Benvenisty: "Fibroblast growth factor 4 and its novel splice isoform have opposing effects on the maintenance of human embryonic stem cell self-renewal." dans: Stem cells (Dayton, Ohio), Vol. 26, Issue 3, pp. 767-74, (2008) (PubMed).

  • Antigène
    FGF4 (Fibroblast Growth Factor 4 (FGF4))
    Autre désignation
    FGF4 (FGF4 Produits)
    Sujet

    Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

    Aliases: HST, KFGF, HST-1, HSTF1, K-FGF, HBGF-4

    Poids moléculaire
    22kDa
    ID gène
    2249
    HGNC
    2249
    UniProt
    P08620
    Pathways
    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance
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