SQSTM1 anticorps (AA 232-356)
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- Antigène Voir toutes SQSTM1 Anticorps
- SQSTM1 (Sequestosome 1 (SQSTM1))
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Épitope
- AA 232-356
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp SQSTM1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- Fonction
- SQSTM1 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.
- Clone
- 5H7E2
- Isotype
- IgG1
- Top Product
- Discover our top product SQSTM1 Anticorps primaire
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma." dans: Cancer science, Vol. 103, Issue 4, pp. 760-6, (2012) (PubMed).
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Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma." dans: Cancer science, Vol. 103, Issue 4, pp. 760-6, (2012) (PubMed).
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- Antigène
- SQSTM1 (Sequestosome 1 (SQSTM1))
- Autre désignation
- SQSTM1 (SQSTM1 Produits)
- Sujet
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Description: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Aliases: p60, p62, A170, OSIL, PDB3, ZIP3, p62B
- Poids moléculaire
- 47.7kDa
- ID gène
- 8878
- HGNC
- 8878
- UniProt
- Q13501
- Pathways
- Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy
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