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SQSTM1 anticorps (AA 232-356)

SQSTM1 Reactivité: Humain WB, IHC, ELISA, FACS Hôte: Souris Monoclonal 5H7E2 unconjugated
N° du produit ABIN1724836
  • Antigène Voir toutes SQSTM1 Anticorps
    SQSTM1 (Sequestosome 1 (SQSTM1))
    Épitope
    • 17
    • 15
    • 11
    • 9
    • 8
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 232-356
    Reactivité
    • 139
    • 58
    • 54
    • 18
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 116
    • 21
    • 1
    • 1
    Souris
    Clonalité
    • 115
    • 24
    Monoclonal
    Conjugué
    • 76
    • 9
    • 8
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SQSTM1 est non-conjugé
    Application
    • 97
    • 51
    • 40
    • 35
    • 22
    • 19
    • 17
    • 16
    • 14
    • 13
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
    Fonction
    SQSTM1 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.
    Clone
    5H7E2
    Isotype
    IgG1
    Top Product
    Discover our top product SQSTM1 Anticorps primaire
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Inoue, Suzuki, Mitsuishi, Miki, Suzuki, Sugawara, Watanabe, Sakurada, Endo, Uruno, Sasano, Nakagawa, Satoh, Tanaka, Kubo, Motohashi, Yamamoto: "Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma." dans: Cancer science, Vol. 103, Issue 4, pp. 760-6, (2012) (PubMed).

  • Antigène
    SQSTM1 (Sequestosome 1 (SQSTM1))
    Autre désignation
    SQSTM1 (SQSTM1 Produits)
    Sujet

    Description: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

    Aliases: p60, p62, A170, OSIL, PDB3, ZIP3, p62B

    Poids moléculaire
    47.7kDa
    ID gène
    8878
    HGNC
    8878
    UniProt
    Q13501
    Pathways
    Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy
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