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NG2 anticorps (AA 2247-2308)

MCSP Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 7G4E5 unconjugated
N° du produit ABIN1724837
  • Antigène Voir toutes NG2 (MCSP) Anticorps
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Épitope
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2247-2308
    Reactivité
    • 45
    • 23
    • 17
    • 1
    Humain
    Hôte
    • 42
    • 14
    Souris
    Clonalité
    • 32
    • 23
    • 1
    Monoclonal
    Conjugué
    • 28
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Cet anticorp NG2 est non-conjugé
    Application
    • 31
    • 20
    • 10
    • 10
    • 8
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Fonction
    CSPG4 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human CSPG4 (AA: 2247-2308) expressed in E. Coli.
    Clone
    7G4E5
    Isotype
    IgG1
  • Indications d'application

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wang, Katayama, Wang, Yu, Favoino, Sakakura, Favole, Tsuchikawa, Silver, Watkins, Kageshita, Ferrone: "Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." dans: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).

    Price, Colvin Wanshura, Yang, Carlson, Xiang, Li, Ferrone, Dudek, Turley, McCarthy: "CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma." dans: Pigment cell & melanoma research, Vol. 24, Issue 6, pp. 1148-57, (2011) (PubMed).

  • Antigène
    NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
    Autre désignation
    CSPG4 (MCSP Produits)
    Sujet

    Description: A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

    Aliases: NG2, MCSP, MCSPG, MSK16, HMW-MAA, MEL-CSPG

    Poids moléculaire
    250.0kDa
    ID gène
    1464
    HGNC
    1464
    UniProt
    Q6UVK1
    Pathways
    Glycosaminoglycan Metabolic Process
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