NG2 anticorps (AA 2247-2308)
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- Antigène Voir toutes NG2 (MCSP) Anticorps
- NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
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Épitope
- AA 2247-2308
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp NG2 est non-conjugé
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Application
- ELISA, Flow Cytometry (FACS)
- Fonction
- CSPG4 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human CSPG4 (AA: 2247-2308) expressed in E. Coli.
- Clone
- 7G4E5
- Isotype
- IgG1
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." dans: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).
: "CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma." dans: Pigment cell & melanoma research, Vol. 24, Issue 6, pp. 1148-57, (2011) (PubMed).
: "
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Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." dans: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).
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- Antigène
- NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))
- Autre désignation
- CSPG4 (MCSP Produits)
- Sujet
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Description: A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.
Aliases: NG2, MCSP, MCSPG, MSK16, HMW-MAA, MEL-CSPG
- Poids moléculaire
- 250.0kDa
- ID gène
- 1464
- HGNC
- 1464
- UniProt
- Q6UVK1
- Pathways
- Glycosaminoglycan Metabolic Process
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