NG2 anticorps (AA 2247-2308)

N° du produit ABIN1724837

Détail du produit anti-NG2 anticorps

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Épitope: AA 2247-2308

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NG2 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Fonction: CSPG4 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CSPG4 (AA: 2247-2308) expressed in E. Coli.

Clone: 7G4E5

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-NG2 (ABIN1724837)

Wang, Katayama, Wang, Yu, Favoino, Sakakura, Favole, Tsuchikawa, Silver, Watkins, Kageshita, Ferrone: "Functional characterization of an scFv-Fc antibody that immunotherapeutically targets the common cancer cell surface proteoglycan CSPG4." dans: Cancer research, Vol. 71, Issue 24, pp. 7410-22, (2011) (PubMed).

Price, Colvin Wanshura, Yang, Carlson, Xiang, Li, Ferrone, Dudek, Turley, McCarthy: "CSPG4, a potential therapeutic target, facilitates malignant progression of melanoma." dans: Pigment cell & melanoma research, Vol. 24, Issue 6, pp. 1148-57, (2011) (PubMed).

Détails sur NG2

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Autre désignation: CSPG4 (MCSP Produits)

Synonymes: anticorps HMW-MAA, anticorps MCSP, anticorps MCSPG, anticorps MEL-CSPG, anticorps MSK16, anticorps NG2, anticorps 4732461B14Rik, anticorps AN2, anticorps Ng2, anticorps HSMCSGEN1, anticorps MCS, anticorps chondroitin sulfate proteoglycan 4, anticorps sperm mitochondria associated cysteine rich protein, anticorps CSPG4, anticorps Cspg4, anticorps SMCP

Sujet:

Description: A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells.

Aliases: NG2, MCSP, MCSPG, MSK16, HMW-MAA, MEL-CSPG

Poids moléculaire: 250.0kDa

ID gène: 1464

HGNC: 1464

UniProt: Q6UVK1

Pathways: Glycosaminoglycan Metabolic Process