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MCAM anticorps (AA 84-189)

Name: MCAM anticorps (AA 84-189)
Brand: antibodies-online
SKU: ABIN1724844
Price: 614.71 EUR
Availability: InStock

MCAM Reactivité: Humain FACS, IHC, WB, ELISA Hôte: Souris Monoclonal 6C3E6 unconjugated

Immunohistochemical analysis of paraffin-embedded liver cancer tissues using MCAM mouse mAb with DAB staining. (MCAM anticorps (AA 84-189))

IHC

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (MCAM anticorps (AA 84-189))

ELISA

Flow cytometric analysis of MCF-7 cells using MCAM mouse mAb (green) and negative control (red). (MCAM anticorps (AA 84-189))

FACS

Western blot analysis using MCAM mouse mAb against HUVE-12 (1), EVC-304 (2), HELA (3) and MCF-7 (4) cell lysate. (MCAM anticorps (AA 84-189))

Western blot analysis using MCAM mAb against human MCAM recombinant protein. (MCAM anticorps (AA 84-189))

Western blot analysis using MCAM mAb against HEK293 (1) and MCAM (AA: 84-189)-hIgGFc transfected HEK293 (2) cell lysate. (MCAM anticorps (AA 84-189))

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using MCAM mouse mAb with DAB staining. (MCAM anticorps (AA 84-189))

IHC

7 images

(2 références)

N° du produit ABIN1724844

Fiche de données

Antigène Voir toutes MCAM Anticorps

MCAM (Melanoma Cell Adhesion Molecule (MCAM))
Épitope
16

13

11

6

4

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 84-189
Reactivité
133

53

47

14

14

9

8

7

6

2
Humain
Hôte
95

62

8

1

1
Souris
Anticorps secondaires appropriés
Clonalité
88

79
Monoclonal
Conjugué
70

14

14

11

6

5

4

4

4

3

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp MCAM est non-conjugé
Application
85

79

68

42

22

20

14

10

10

5

4

4

3

3

2

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Fonction

MCAM Antibody

Purification

Purified antibody

Immunogène

Purified recombinant fragment of human MCAM (AA: 84-189) expressed in E. Coli.

Clone

6C3E6

Isotype

IgG1
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MCAM Reactivité: Humain FACS, WB, IF, ELISA Hôte: Souris Monoclonal 4D10C7 unconjugated

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MCAM Reactivité: Humain IHC, WB, IF Hôte: Lapin Polyclonal unconjugated

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MCAM Reactivité: Humain FACS, IHC, WB, IF, ELISA Hôte: Lapin Monoclonal 8A10 unconjugated Recombinant Antibody

anti-Melanoma Cell Adhesion Molecule (MCAM) antibody
MCAM Reactivité: Humain, Souris, Rat IHC Hôte: Lapin Polyclonal unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 1-646) antibody
MCAM Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 226-374) antibody
MCAM Reactivité: Humain IHC, StM Hôte: Souris Monoclonal MCAM-3046 unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) antibody
MCAM Reactivité: Humain, Souris, Rat IHC, WB Hôte: Lapin Polyclonal unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) antibody
MCAM Reactivité: Humain, Souris, Lapin, Chien FACS, WB, IHC (p), IP, IHC (fro), ICC Hôte: Souris Monoclonal P1H12 unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 201-300) antibody
MCAM Reactivité: Humain, Rat FACS, WB, ELISA, IHC (p) Hôte: Lapin Polyclonal unconjugated

anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 161-189) antibody
MCAM Reactivité: Humain FACS, WB, IHC (p) Hôte: Lapin Polyclonal RB20606 unconjugated

Indications d'application

ELISA: 1/10000
FCM: 1/200 - 1/400

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Wang, Yan: "CD146, a multi-functional molecule beyond adhesion." dans: Cancer letters, Vol. 330, Issue 2, pp. 150-62, (2013) (PubMed).

Jouve, Despoix, Espeli, Gauthier, Cypowyj, Fallague, Schiff, Dignat-George, Vély, Leroyer: "The involvement of CD146 and its novel ligand Galectin-1 in apoptotic regulation of endothelial cells." dans: The Journal of biological chemistry, Vol. 288, Issue 4, pp. 2571-9, (2013) (PubMed).
Antigène

MCAM (Melanoma Cell Adhesion Molecule (MCAM))

Autre désignation

MCAM (MCAM Produits)

Synonymes

anticorps CD146, anticorps MUC18, anticorps Muc18, anticorps 1-gicerin, anticorps AV025631, anticorps CD149, anticorps s-endo, anticorps s-gicerin, anticorps cd146, anticorps gicerin, anticorps id:ibd3512, anticorps mcam, anticorps MCAM, anticorps melanoma cell adhesion molecule, anticorps melanoma cell adhesion molecule b, anticorps MCAM, anticorps Mcam, anticorps mcamb

Sujet

Description: The protein encoded by this gene plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.

Aliases: CD146, MUC18

Poids moléculaire

71.6kDa

ID gène

4162

HGNC

4162

UniProt

P43121