FLIP anticorps (AA 100-251)
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- Antigène Voir toutes FLIP (CFLAR) Anticorps
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
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Épitope
- AA 100-251
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp FLIP est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Fonction
- CFLAR Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. Coli.
- Clone
- 7A3D12
- Isotype
- IgG1
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence." dans: PLoS ONE, Vol. 7, Issue 9, pp. e44917, (2012) (PubMed).
: "The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition." dans: Cancer prevention research (Philadelphia, Pa.), Vol. 5, Issue 4, pp. 612-20, (2012) (PubMed).
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Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence." dans: PLoS ONE, Vol. 7, Issue 9, pp. e44917, (2012) (PubMed).
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- Antigène
- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
- Autre désignation
- CFLAR (CFLAR Produits)
- Sujet
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Description: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
Aliases: CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1
- Poids moléculaire
- 55kDa
- ID gène
- 8837
- HGNC
- 8837
- UniProt
- O15519
- Pathways
- Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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