FLIP anticorps (AA 100-251)

N° du produit ABIN1724850

Détail du produit anti-FLIP anticorps

Antigène: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Épitope: AA 100-251

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FLIP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Purification: purified

Immunogène: Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. coli.

Clone: 7A3D12

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-FLIP (ABIN1724850)

Bedolla, Gong, Prihoda, Yeh, Thompson, Ghosh, Kumar: "Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence." dans: PLoS ONE, Vol. 7, Issue 9, pp. e44917, (2012) (PubMed).

Li, Ren, Yue, Chen, Khuri, Sun: "The novel Akt inhibitor API-1 induces c-FLIP degradation and synergizes with TRAIL to augment apoptosis independent of Akt inhibition." dans: Cancer prevention research (Philadelphia, Pa.), Vol. 5, Issue 4, pp. 612-20, (2012) (PubMed).

Détails sur FLIP

Antigène: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Autre désignation: CFLAR (CFLAR Produits)

Synonymes: anticorps Clarp1, anticorps cflar, anticorps CFLAR, anticorps FLIP, anticorps CASH, anticorps CASP8AP1, anticorps CLARP, anticorps Casper, anticorps FLAME, anticorps FLAME-1, anticorps FLAME1, anticorps I-FLICE, anticorps MRIT, anticorps c-FLIP, anticorps c-FLIPL, anticorps c-FLIPR, anticorps c-FLIPS, anticorps 2310024N18Rik, anticorps A430105C05Rik, anticorps Cash, anticorps ENSMUSG00000072980, anticorps Flip, anticorps Gm9845, anticorps c-Flip, anticorps CASP8 and FADD-like apoptosis regulator a, anticorps CASP8 and FADD like apoptosis regulator, anticorps CASP8 and FADD like apoptosis regulator S homeolog, anticorps CASP8 and FADD-like apoptosis regulator, anticorps cflara, anticorps CFLAR, anticorps cflar, anticorps cflar.S, anticorps Cflar

Sujet:

Description: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. , , ,

Aliases: CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1

Poids moléculaire: 55 kDa

ID gène: 8837

HGNC: 8837

Pathways: Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development