IL3RA anticorps (AA 200-305)

N° du produit ABIN1724855

Détail du produit anti-IL3RA anticorps

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Épitope: AA 200-305

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL3RA est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Fonction: IL3RA Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human IL3RA (AA: 200-305) expressed in E. Coli.

Clone: 8E11C5

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-IL3RA (ABIN1724855)

Venkataraman, Aguhar, Kreitman, Yuan, Stetler-Stevenson: "Characteristic CD103 and CD123 expression pattern defines hairy cell leukemia: usefulness of CD123 and CD103 in the diagnosis of mature B-cell lymphoproliferative disorders." dans: American journal of clinical pathology, Vol. 136, Issue 4, pp. 625-30, (2011) (PubMed).

Yue, Fu, Wang, Li, Hu, Fu, Shao: "Expression of CD123 and CD114 on the bone marrow cells of patients with myelodysplastic syndrome." dans: Chinese medical journal, Vol. 123, Issue 15, pp. 2034-7, (2010) (PubMed).

Détails sur IL3RA

Antigène: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Autre désignation: IL3RA (IL3RA Produits)

Synonymes: anticorps CD123, anticorps IL3R, anticorps IL3RAY, anticorps IL3RX, anticorps IL3RY, anticorps hIL-3Ra, anticorps CDw123, anticorps SUT-1, anticorps Cyrl, anticorps interleukin 3 receptor subunit alpha, anticorps interleukin 3 receptor, alpha chain, anticorps IL3RA, anticorps Il3ra

Sujet:

Description: The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found.

Aliases: IL3R, CD123, IL3RX, IL3RY, IL3RAY, hIL-3Ra

Poids moléculaire: 43.3kDa

ID gène: 3563

HGNC: 3563

UniProt: P26951

Pathways: Signalistation JAK/STAT