Dynamin 1-Like anticorps (AA 69-213)
-
- Antigène Voir toutes Dynamin 1-Like (DNM1L) Anticorps
- Dynamin 1-Like (DNM1L)
-
Épitope
- AA 69-213
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp Dynamin 1-Like est non-conjugé
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Fonction
- DNM1L Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.
- Clone
- 4E11B11
- Isotype
- IgG1
-
-
- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model." dans: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012) (PubMed).
: "Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension." dans: Circulation research, Vol. 110, Issue 11, pp. 1484-97, (2012) (PubMed).
: "
-
Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model." dans: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012) (PubMed).
-
- Antigène
- Dynamin 1-Like (DNM1L)
- Autre désignation
- DNM1L (DNM1L Produits)
- Sujet
-
Description: The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
Aliases: DLP1, DRP1, DVLP, EMPF, VPS1, DYMPLE, HDYNIV, DYNIV-11
- Poids moléculaire
- 81.9kDa
- ID gène
- 10059
- HGNC
- 10059
- UniProt
- O00429
-