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Dynamin 1-Like anticorps (AA 69-213)

DNM1L Reactivité: Humain WB, ELISA, IHC Hôte: Souris Monoclonal 4E11B11 unconjugated
N° du produit ABIN1724863
  • Antigène Voir toutes Dynamin 1-Like (DNM1L) Anticorps
    Dynamin 1-Like (DNM1L)
    Épitope
    • 23
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 69-213
    Reactivité
    • 51
    • 45
    • 28
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 59
    • 7
    Souris
    Clonalité
    • 59
    • 7
    Monoclonal
    Conjugué
    • 32
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Dynamin 1-Like est non-conjugé
    Application
    • 33
    • 27
    • 17
    • 13
    • 13
    • 12
    • 9
    • 9
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Fonction
    DNM1L Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.
    Clone
    4E11B11
    Isotype
    IgG1
  • Indications d'application
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Thomas, Jacobson: "Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model." dans: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012) (PubMed).

    Marsboom, Toth, Ryan, Hong, Wu, Fang, Thenappan, Piao, Zhang, Pogoriler, Chen, Morrow, Weir, Rehman, Archer: "Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension." dans: Circulation research, Vol. 110, Issue 11, pp. 1484-97, (2012) (PubMed).

  • Antigène
    Dynamin 1-Like (DNM1L)
    Autre désignation
    DNM1L (DNM1L Produits)
    Sujet

    Description: The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.

    Aliases: DLP1, DRP1, DVLP, EMPF, VPS1, DYMPLE, HDYNIV, DYNIV-11

    Poids moléculaire
    81.9kDa
    ID gène
    10059
    HGNC
    10059
    UniProt
    O00429
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