PLAGL1 anticorps (AA 118-222)

N° du produit ABIN1724868

Détail du produit anti-PLAGL1 anticorps

Antigène: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Épitope: AA 118-222

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLAGL1 est non-conjugé

Application: ELISA

Fonction: PLAGL1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PLAGL1 (AA: 118-222) expressed in E. Coli.

Clone: 8F9D12

Isotype: IgG2b

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-PLAGL1 (ABIN1724868)

Liu, Hsieh, Liu, Chang, Lin, Wang, Huang: "Zac1, an Sp1-like protein, regulates human p21(WAF1/Cip1) gene expression in HeLa cells." dans: Experimental cell research, Vol. 317, Issue 20, pp. 2925-37, (2011) (PubMed).

Détails sur PLAGL1

Antigène: PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))

Autre désignation: PLAGL1 (PLAGL1 Produits)

Synonymes: anticorps PLAGL1, anticorps LOT1, anticorps ZAC, anticorps ZAC1, anticorps Lot1, anticorps Zac1, anticorps PLAG1 like zinc finger 1, anticorps uncharacterized LOC100350914, anticorps pleiomorphic adenoma gene-like 1, anticorps PLAGL1, anticorps LOC100350914, anticorps Plagl1

Sujet:

Description: This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene.

Aliases: ZAC, LOT1, ZAC1

Poids moléculaire: 50.8kDa

ID gène: 5325

HGNC: 5325

UniProt: Q9UM63