PLAGL1 anticorps (AA 118-222)
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- Antigène Voir toutes PLAGL1 Anticorps
- PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
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Épitope
- AA 118-222
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PLAGL1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human PLAGL1 (AA: 118-222) expressed in E. coli.
- Clone
- 8D8C5
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Zac1, an Sp1-like protein, regulates human p21(WAF1/Cip1) gene expression in HeLa cells." dans: Experimental cell research, Vol. 317, Issue 20, pp. 2925-37, (2011) (PubMed).
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Zac1, an Sp1-like protein, regulates human p21(WAF1/Cip1) gene expression in HeLa cells." dans: Experimental cell research, Vol. 317, Issue 20, pp. 2925-37, (2011) (PubMed).
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- Antigène
- PLAGL1 (Pleiomorphic Adenoma Gene-Like 1 (PLAGL1))
- Autre désignation
- PLAGL1 (PLAGL1 Produits)
- Synonymes
- anticorps PLAGL1, anticorps LOT1, anticorps ZAC, anticorps ZAC1, anticorps Lot1, anticorps Zac1, anticorps PLAG1 like zinc finger 1, anticorps uncharacterized LOC100350914, anticorps pleiomorphic adenoma gene-like 1, anticorps PLAGL1, anticorps LOC100350914, anticorps Plagl1
- Sujet
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Description: This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene. ,
Aliases: ZAC, LOT1, ZAC1
- Poids moléculaire
- 50.8 kDa
- ID gène
- 5325
- HGNC
- 5325
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