CA9 anticorps (AA 37-186)
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- Antigène Voir toutes CA9 Anticorps
- CA9 (Carbonic Anhydrase IX (CA9))
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Épitope
- AA 37-186
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CA9 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Fonction
- CA9 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human CA9 (AA: 37-186) expressed in E. Coli.
- Clone
- 7C4A5
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer." dans: Breast cancer research and treatment, Vol. 136, Issue 1, pp. 67-75, (2012) (PubMed).
: "GLUT1 and CAIX expression profiles in breast cancer correlate with adverse prognostic factors and MCT1 overexpression." dans: Histology and histopathology, Vol. 26, Issue 10, pp. 1279-86, (2011) (PubMed).
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Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer." dans: Breast cancer research and treatment, Vol. 136, Issue 1, pp. 67-75, (2012) (PubMed).
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- Antigène
- CA9 (Carbonic Anhydrase IX (CA9))
- Autre désignation
- CA9 (CA9 Produits)
- Sujet
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Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
Aliases: MN, CAIX
- Poids moléculaire
- 49.7kDa
- ID gène
- 768
- HGNC
- 768
- UniProt
- Q16790
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