CD22 anticorps (AA 621-725)
(2 références)-
- Antigène Voir toutes CD22 Anticorps
- CD22 (CD22 Molecule (CD22))
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Épitope
- AA 621-725
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD22 est non-conjugé
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Application
- Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- Fonction
- CD22 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human CD22 (AA: 621-725) expressed in E. Coli.
- Clone
- 2H1C4
- Isotype
- IgG1
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anti-CD22 Molecule (CD22) (AA 621-725) antibody
CD22 Reactivité: Humain FACS, ELISA, ICC Hôte: Souris Monoclonal 1A3A11 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reactivité: Humain FACS, WB, ELISA, IHC, IF, Coat, StM Hôte: Souris Monoclonal BLCAM-1795 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reactivité: Humain FACS, WB, ELISA, IHC, IF, Coat Hôte: Souris Monoclonal BLCAM-1796 unconjugated
anti-CD22 Molecule (CD22) antibodyCD22 Reactivité: Humain, Non-Human Primate FACS, WB, IP Hôte: Souris Monoclonal MEM-01 unconjugated
anti-CD22 Molecule (CD22) antibody (PE)CD22 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal MEM-01 PE
anti-CD22 Molecule (CD22) antibody (FITC)CD22 Reactivité: Humain FACS Hôte: Souris Monoclonal IS7 FITC
anti-CD22 Molecule (CD22) (AA 708-847) antibodyCD22 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-CD22 Molecule (CD22) antibodyCD22 Reactivité: Humain, Souris, Rat, Singe, Chien WB, IHC, IHC (p) Hôte: Souris Monoclonal 4C3 unconjugated
anti-CD22 Molecule (CD22) (AA 20-687) antibodyCD22 Reactivité: Humain FACS, WB, ELISA, IF, IP Hôte: Lapin Monoclonal DM13 unconjugated
anti-CD22 Molecule (CD22) (AA 52-178) antibodyCD22 Reactivité: Humain IHC Hôte: Lapin Monoclonal MSVA-022R unconjugated Recombinant Antibody
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- Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "CD22 antigen is broadly expressed on lung cancer cells and is a target for antibody-based therapy." dans: Cancer research, Vol. 72, Issue 21, pp. 5556-65, (2012) (PubMed).
: "CD22 regulates adaptive and innate immune responses of B cells." dans: Journal of innate immunity, Vol. 3, Issue 4, pp. 411-9, (2011) (PubMed).
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: "CD22 antigen is broadly expressed on lung cancer cells and is a target for antibody-based therapy." dans: Cancer research, Vol. 72, Issue 21, pp. 5556-65, (2012) (PubMed).
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- Antigène
- CD22 (CD22 Molecule (CD22))
- Autre désignation
- CD22 (CD22 Produits)
- Sujet
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Description: CD22 may be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules
Aliases: SIGLEC2, SIGLEC-2
- Poids moléculaire
- 95.3kDa
- ID gène
- 933
- HGNC
- 933
- UniProt
- P20273
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