SERPINA7 anticorps (AA 168-302)

N° du produit ABIN1724894

Détail du produit anti-SERPINA7 anticorps

Antigène: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Épitope: AA 168-302

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SERPINA7 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: SERPINA7 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human SERPINA7 (AA: 168-302) expressed in E. Coli.

Clone: 5B11E9

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-SERPINA7 (ABIN1724894)

Yan, Yan, Ou: "Human thyroxine binding globulin (TBG) promoter directs efficient and sustaining transgene expression in liver-specific pattern." dans: Gene, Vol. 506, Issue 2, pp. 289-94, (2012) (PubMed).

Duhan, Patston: "Explanation for the high heat stability of thyroxine binding globulin-Chicago." dans: Endocrine regulations, Vol. 44, Issue 2, pp. 43-7, (2010) (PubMed).

Détails sur SERPINA7

Antigène: SERPINA7 (Serpin Family A Member 7 (SERPINA7))

Autre désignation: SERPINA7 (SERPINA7 Produits)

Sujet:

Description: There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Aliases: TBG

Poids moléculaire: 46.3kDa

ID gène: 6906

HGNC: 6906

UniProt: P05543

Pathways: Hormone Transport