DIS3L2 anticorps (AA 27-250)

N° du produit ABIN1724900

Détail du produit anti-DIS3L2 anticorps

Antigène: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Épitope: AA 27-250

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DIS3L2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Fonction: DIS3L2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human DIS3L2 (AA: 27-250) expressed in E. Coli.

Clone: 6C7B2

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-DIS3L2 (ABIN1724900)

Du Toit: "Cytoskeleton: Formins induce nuclear actin assembly." dans: Nature reviews. Molecular cell biology, Vol. 14, Issue 6, pp. 328, (2013) (PubMed).

Astuti, Morris, Cooper, Staals, Wake, Fews, Gill, Gentle, Shuib, Ricketts, Cole, van Essen, van Lingen, Neri, Opitz, Rump, Stolte-Dijkstra, Müller, Pruijn, Latif, Maher: "Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility." dans: Nature genetics, Vol. 44, Issue 3, pp. 277-84, (2012) (PubMed).

Détails sur DIS3L2

Antigène: DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Autre désignation: DIS3L2 (DIS3L2 Produits)

Synonymes: anticorps RGD1560168, anticorps DIS3L2, anticorps DKFZp469O0522, anticorps FAM6A, anticorps PRLMNS, anticorps hDIS3L2, anticorps 4930429A22Rik, anticorps 8030493P09Rik, anticorps DIS3-like 3'-5' exoribonuclease 2, anticorps DIS3 like 3'-5' exoribonuclease 2, anticorps DIS3-like exonuclease 2, anticorps Dis3l2, anticorps DIS3L2, anticorps LOC100344728

Sujet:

Description: The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene.

Aliases: FAM6A, PRLMNS

Poids moléculaire: 99.3kDa

ID gène: 129563

HGNC: 129563

UniProt: Q8IYB7

Pathways: Stem Cell Maintenance