IGFBP7 anticorps (AA 52-156)

N° du produit ABIN1724903

Détail du produit anti-IGFBP7 anticorps

Antigène: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Épitope: AA 52-156

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGFBP7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: purified

Immunogène: Purified recombinant fragment of human IGFBP7 (AA: 52-156) expressed in E. coli.

Clone: 1D9E7

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-IGFBP7 (ABIN1724903)

Evdokimova, Tognon, Benatar, Yang, Krutikov, Pollak, Sorensen, Seth: "IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors." dans: Science signaling, Vol. 5, Issue 255, pp. ra92, (2012) (PubMed).

Détails sur IGFBP7

Antigène: IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))

Autre désignation: IGFBP7 (IGFBP7 Produits)

Synonymes: anticorps zgc:85888, anticorps AGM, anticorps FSTL2, anticorps IBP-7, anticorps IGFBP-7, anticorps IGFBP-7v, anticorps IGFBPRP1, anticorps MAC25, anticorps PSF, anticorps RAMSVPS, anticorps TAF, anticorps Fstl2, anticorps Mac25, anticorps insulin like growth factor binding protein 7, anticorps insulin-like growth factor binding protein 7, anticorps IGFBP7, anticorps igfbp7, anticorps Igfbp7

Sujet:

Description: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). ,

Aliases: AGM, PSF, TAF, FSTL2, IBP-7, MAC25, IGFBP-7, RAMSVPS, IGFBP-7v, IGFBPRP1

Poids moléculaire: 29.1 kDa

ID gène: 3490

HGNC: 3490

Pathways: Growth Factor Binding