IGFBP7 anticorps (AA 52-156)
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- Antigène Voir toutes IGFBP7 Anticorps
- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
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Épitope
- AA 52-156
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp IGFBP7 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC)
- Fonction
- IGFBP7 Antibody
- Purification
- Purified antibody
- Immunogène
- Purified recombinant fragment of human IGFBP7 (AA: 52-156) expressed in E. Coli.
- Clone
- 1D9E7
- Isotype
- IgG1
- Top Product
- Discover our top product IGFBP7 Anticorps primaire
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- Indications d'application
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors." dans: Science signaling, Vol. 5, Issue 255, pp. ra92, (2012) (PubMed).
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IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors." dans: Science signaling, Vol. 5, Issue 255, pp. ra92, (2012) (PubMed).
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- Antigène
- IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
- Autre désignation
- IGFBP7 (IGFBP7 Produits)
- Sujet
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Description: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).
Aliases: AGM, PSF, TAF, FSTL2, IBP-7, MAC25, IGFBP-7, RAMSVPS, IGFBP-7v, IGFBPRP1
- Poids moléculaire
- 29.1kDa
- ID gène
- 3490
- HGNC
- 3490
- UniProt
- Q16270
- Pathways
- Growth Factor Binding
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