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IGFBP7 anticorps (AA 52-156)

IGFBP7 Reactivité: Humain ELISA, IHC Hôte: Souris Monoclonal 1D9E7 unconjugated
N° du produit ABIN1724903
  • Antigène Voir toutes IGFBP7 Anticorps
    IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
    Épitope
    • 15
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 52-156
    Reactivité
    • 55
    • 30
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 3
    • 2
    • 1
    Souris
    Clonalité
    • 53
    • 6
    • 1
    Monoclonal
    Conjugué
    • 27
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IGFBP7 est non-conjugé
    Application
    • 37
    • 19
    • 13
    • 13
    • 12
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Fonction
    IGFBP7 Antibody
    Purification
    Purified antibody
    Immunogène
    Purified recombinant fragment of human IGFBP7 (AA: 52-156) expressed in E. Coli.
    Clone
    1D9E7
    Isotype
    IgG1
    Top Product
    Discover our top product IGFBP7 Anticorps primaire
  • Indications d'application
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Evdokimova, Tognon, Benatar, Yang, Krutikov, Pollak, Sorensen, Seth: "IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors." dans: Science signaling, Vol. 5, Issue 255, pp. ra92, (2012) (PubMed).

  • Antigène
    IGFBP7 (Insulin-Like Growth Factor Binding Protein 7 (IGFBP7))
    Autre désignation
    IGFBP7 (IGFBP7 Produits)
    Sujet

    Description: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307).

    Aliases: AGM, PSF, TAF, FSTL2, IBP-7, MAC25, IGFBP-7, RAMSVPS, IGFBP-7v, IGFBPRP1

    Poids moléculaire
    29.1kDa
    ID gène
    3490
    HGNC
    3490
    UniProt
    Q16270
    Pathways
    Growth Factor Binding
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