Dynamin 1-Like anticorps (AA 69-213)

N° du produit ABIN1724907

Détail du produit anti-Dynamin 1-Like anticorps

Antigène: Dynamin 1-Like (DNM1L)

Épitope: AA 69-213

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Dynamin 1-Like est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Fonction: DNM1L Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human DNM1L (AA: 69-213) expressed in E. Coli.

Clone: 4A4C7

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-Dynamin 1-Like (ABIN1724907)

Thomas, Jacobson: "Defects in mitochondrial fission protein dynamin-related protein 1 are linked to apoptotic resistance and autophagy in a lung cancer model." dans: PLoS ONE, Vol. 7, Issue 9, pp. e45319, (2012) (PubMed).

Marsboom, Toth, Ryan, Hong, Wu, Fang, Thenappan, Piao, Zhang, Pogoriler, Chen, Morrow, Weir, Rehman, Archer: "Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension." dans: Circulation research, Vol. 110, Issue 11, pp. 1484-97, (2012) (PubMed).

Détails sur Dynamin 1-Like

Antigène: Dynamin 1-Like (DNM1L)

Autre désignation: DNM1L (DNM1L Produits)

Synonymes: anticorps DLP1, anticorps DRP1, anticorps DVLP, anticorps DYMPLE, anticorps EMPF, anticorps HDYNIV, anticorps 6330417M19Rik, anticorps AI450666, anticorps Dlp1, anticorps Dnmlp1, anticorps Drp1, anticorps python, anticorps Dnml1, anticorps dnm1l, anticorps MGC53850, anticorps zgc:66163, anticorps DNM1L, anticorps 18.m06247, anticorps CG3210, anticorps DRP, anticorps Dmel\CG3210, anticorps Dnm1/Drp1, anticorps Drp, anticorps Drp-1, anticorps drp-1, anticorps drp1, anticorps frat, anticorps l(2)22Fc, anticorps l(2)22Fd, anticorps l(2)ND2, anticorps l(2)ND3, anticorps dynamin 1 like, anticorps dynamin 1-like, anticorps dynamin 1-like L homeolog, anticorps dynamin-1-like, anticorps dynamin-1-like protein, anticorps dynamin-like protein, anticorps Dynamin related protein 1, anticorps DNM1L, anticorps Dnm1l, anticorps dnm1l.L, anticorps dnm1l, anticorps LOC100369408, anticorps LOC411472, anticorps dyn1, anticorps cgd1_580, anticorps EHI_052740, anticorps PVX_092875, anticorps BBOV_II002980, anticorps Drp1

Sujet:

Description: The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.

Aliases: DLP1, DRP1, DVLP, EMPF, VPS1, DYMPLE, HDYNIV, DYNIV-11

Poids moléculaire: 81.9kDa

ID gène: 10059

HGNC: 10059

UniProt: O00429