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MLXIPL anticorps (AA 18-143)

MLXIPL Reactivité: Humain ELISA, ICC Hôte: Souris Monoclonal 5D12D1 unconjugated
N° du produit ABIN1724913
  • Antigène Voir toutes MLXIPL Anticorps
    MLXIPL (MLX Interacting Protein-Like (MLXIPL))
    Épitope
    • 15
    • 14
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 18-143
    Reactivité
    • 41
    • 24
    • 12
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 54
    • 2
    Souris
    Clonalité
    • 54
    • 2
    Monoclonal
    Conjugué
    • 23
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MLXIPL est non-conjugé
    Application
    • 31
    • 20
    • 18
    • 13
    • 13
    • 10
    • 8
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunocytochemistry (ICC)
    Fonction
    MLXIPL Antibody
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human MLXIPL (AA: 18-143) expressed in E. Coli.
    Clone
    5D12D1
    Isotype
    IgG1
  • Indications d'application

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Noordeen, Meur, Rutter, Leclerc: "Glucose-induced nuclear shuttling of ChREBP is mediated by sorcin and Ca(2+) ions in pancreatic β-cells." dans: Diabetes, Vol. 61, Issue 3, pp. 574-85, (2012) (PubMed).

    Hurtado del Pozo, Vesperinas-García, Rubio, Corripio-Sánchez, Torres-García, Obregon, Calvo: "ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity." dans: Biochimica et biophysica acta, Vol. 1811, Issue 12, pp. 1194-200, (2011) (PubMed).

  • Antigène
    MLXIPL (MLX Interacting Protein-Like (MLXIPL))
    Autre désignation
    MLXIPL (MLXIPL Produits)
    Synonymes
    anticorps ChREBP, anticorps MLXIPL, anticorps CHREBP, anticorps MIO, anticorps MONDOB, anticorps WBSCR14, anticorps WS-bHLH, anticorps bHLHd14, anticorps Wbscr14, anticorps MLX interacting protein-like, anticorps MLX interacting protein like, anticorps MLXIPL, anticorps Mlxipl
    Sujet

    Description: This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.



    Aliases: MIO, CHREBP, MONDOB, WBSCR14, WS-bHLH, bHLHd14

    Poids moléculaire
    93.1kDa
    ID gène
    51085
    HGNC
    51085
    UniProt
    Q9NP71
    Pathways
    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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