DARPP32 anticorps (AA 95-204)
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- Antigène Voir toutes DARPP32 (PPP1R1B) Anticorps
- DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))
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Épitope
- AA 95-204
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp DARPP32 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human PPP1R1B (AA: 95-204) expressed in E. coli.
- Clone
- 2G6D9
- Isotype
- IgG1
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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Detailed DARPP-32 expression profiles in postmortem brains from patients with schizophrenia: an immunohistochemical study." dans: Medical molecular morphology, Vol. 44, Issue 4, pp. 190-9, (2011) (PubMed).
: "Both t-Darpp and DARPP-32 can cause resistance to trastuzumab in breast cancer cells and are frequently expressed in primary breast cancers." dans: Breast cancer research and treatment, Vol. 120, Issue 1, pp. 47-57, (2010) (PubMed).
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Detailed DARPP-32 expression profiles in postmortem brains from patients with schizophrenia: an immunohistochemical study." dans: Medical molecular morphology, Vol. 44, Issue 4, pp. 190-9, (2011) (PubMed).
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- Antigène
- DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))
- Autre désignation
- PPP1R1B (PPP1R1B Produits)
- Synonymes
- anticorps darpp32, anticorps darpp-32, anticorps Darpp-32, anticorps Darpp32, anticorps DARPP-32, anticorps DARPP32, anticorps AU040756, anticorps protein phosphatase 1 regulatory inhibitor subunit 1B, anticorps protein phosphatase 1, regulatory (inhibitor) subunit 1B, anticorps protein phosphatase 1 regulatory inhibitor subunit 1B S homeolog, anticorps ppp1r1b, anticorps PPP1R1B, anticorps Ppp1r1b, anticorps ppp1r1b.S
- Sujet
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Description: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. ,
Aliases: DARPP32, DARPP-32
- Poids moléculaire
- 23 kDa
- ID gène
- 84152
- HGNC
- 84152
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